Cell Factories for Industrial Production Processes: Current Issues and Emerging Solutions

Processes

卷:8

Alessandra Procentese¹  Irene Hjorth Jacobsen¹  José Luis Martínez¹  Clara Navarrete¹ 

[1] Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, 2800 Kongens Lyngby, Denmark;

关键词: cell factory;    lignocellulosic biomass;    biomass pretreatment;    lignocellulosic inhibitors;    Yarrowia lipolytica;    Trichosporon oleaginosus;   

DOI  :  10.3390/pr8070768

来源: DOAJ

【 摘 要 】

Despite all the progresses made by metabolic engineering, still only a few biotechnological processes are running at an industrial level. In order to boost the biotechnological sector, integration strategies as well as long-term views are needed. The aim of the present review is to identify the main drawbacks in biotechnological processes, and to propose possible solutions to overcome the issues in question. Novel cell factories and bioreactor design are discussed as possible solutions. In particular, the following microorganisms: Yarrowia lipolytica, Trichosporon oleaginosus, Ustilago cynodontis, Debaryomyces hansenii along with sequential bioreactor configurations are presented as possible cell factories and bioreactor design solutions, respectively.

【 授权许可】

Unknown