Orthostatic variation of pulmonary artery pressure in ambulatory heart failure patients

BMC Cardiovascular Disorders

Research

Prince Sethi¹  Kartik Munshi¹  Andrew J. Sauer¹  Sagar Ranka¹  Brianna Stack¹  Kamal Gupta¹  Prakash Acharya¹  Zubair Shah¹  Payton Lancaster¹ 

[1] Department of Cardiovascular Disease, University of Kansas Medical Center, 3901 Rainbow Blvd, 66160, Kansas City, KS, USA;

关键词: Orthostatic variation;    Pulmonary artery pressure;    CardioMEMS;    Heart failure;   

DOI  :  10.1186/s12872-023-03534-y

 received in 2023-05-29, accepted in 2023-09-26,  发布年份 2023

来源: Springer

【 摘 要 】

AimTo study effect of change in position (supine and standing) on pulmonary artery pressure (PAP) in ambulatory heart failure (HF) patients.MethodsSeventeen patients with CardioMEMS® sensor and stable heart failure were consented and included in this single center study. Supine and standing measurements were obtained with at least 5 min interval between the two positions. These measurements included PAP readings utilizing the manufacturer handheld interrogator obtaining 10 s data in addition to the systemic blood pressure and heart rate recordings.ResultsMean supine and standing readings and their difference (Δ) were as follows respectively: Systolic PAP were 33.4 (± 11.19), 23.6 (± 10) and Δ was 9.9 mmHg (p = 0.0001), diastolic PAP were 14.2 (± 5.6), 7.9 (± 5.7) and Δ was 6.3 mmHg (p = 0.0001) and mean PAP were 21.8 (± 7.8), 14 (± 7.2) and Δ was 7.4 mmHg (p = 0.0001) while the systemic blood pressure did not vary significantly.ConclusionThere is orthostatic variation of PAP in ambulatory HF patients demonstrating a mean decline with standing in diastolic PAP by 6.3 mmHg, systolic PAP by 9.9 mmHg and mean PAP by 7.4 mmHg in absence of significant orthostatic variation in systemic blood pressure or heart rate. These findings have significant clinical implications and inform that PAP in each patient should always be measured in the same position. Since initial readings at the time of implant were taken in supine position, it may be best to use supine position or to obtain a baseline standing PAP reading if standing PAP is planned on being used.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

【 图 表 】

12951_2015_111_Article_IEq1.gif