Multiparametric cardiac magnetic resonance imaging (CMR) for the diagnosis of Loeffler’s endocarditis: a case report

BMC Cardiovascular Disorders

Case Report

Patrick Behm¹  Malte Kelm¹  Mareike Gastl¹  Florian Bönner¹  Christoph Jacoby¹ 

[1] Department of Cardiology, Pulmonology and Vascular Medicine, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany;

关键词: CMR;    Restrictive cardiomyopathy;    Loeffler’s endocarditis;    Heart failure;    Hypereosinophilic syndrome;    Fibrosis;    Case report;   

DOI  :  10.1186/s12872-017-0492-7

 received in 2016-09-07, accepted in 2017-02-03,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundEndocarditis parietalis fibroplastica Löfflein (EPF) is a rare form of primary restrictive cardiomyopathy with poor prognosis. It is generally caused by hypereosinophilic syndrome with eosinophilic penetration of the heart. This leads to congestive heart failure in three different stages. As a frequent manifestation of neoplastic diseases, cardiac involvement means poor prognosis.Case presentationThe present report deals with a case of EPF caused by non-specified T-cell lymphoma (T-NOS). Besides an elevated Troponin-T enzyme, the electrocardiogram and the transthoracic echocardiography did not show any characteristic results. Due to risk/benefit assessment and low thrombocyte amounts, endomyocardial biopsy and catheterization were discarded. Using cardiovascular magnetic resonance (CMR) with steady-state free precession sequences, T2-mappping, strain analysis and late gadolinium enhancement, we were able to clearly highlight cardiac involvement at different stages. These findings characterized T-NOS as a palliative situation.ConclusionMultiparametric CMR can not only identify EPF but also characterize the patchy disease state. This provides an individual prognosis assessment. Aside from prognosis estimation, it can also be used for therapy monitoring.

【 授权许可】

CC BY   
© The Author(s). 2017