Peripheral artery disease in peritoneal dialysis and hemodialysis patients: single-center retrospective study in Taiwan

BMC Nephrology

Research Article

Chun-Chuan Lee¹  Li-Hua Chou²  Sheng-Fang Chiang²  Pi-Chu Jen²  Mei-Ching Yeh²  Su-Mei Shen²  Chih-Jen Wu³  Chi-Feng Pan⁴ 

[1] Division of Endocrinology and Metabolism, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan;Division of Hemodialysis and Peritoneal Dialysis, Department of Nursing, Mackay Memorial Hospital, Taipei, Taiwan;Division of Nephrology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan;College of Medicine, Taipei Medical University, Taipei, Taiwan;Division of Nephrology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan;Mackay Medicine, Nursing and Management College, Taipei, Taiwan;

关键词: Ankle-brachial pressure index (ABI);    Cardiovascular disease;    End-stage renal disease;    Hemodialysis;    Peritoneal dialysis;    Peripheral artery disease;   

DOI  :  10.1186/1471-2369-13-100

 received in 2012-05-04, accepted in 2012-08-27,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundPeripheral artery disease (PAD) is a condition characterized by restricted blood flow to the extremities, and is especially common in the elderly. PAD increases the risk for mortality and morbidity in patients with end-stage renal disease (ESRD), especially those on hemodialysis (HD).MethodsThe records of 484 patients with end-stage renal disease who were on HD or peritoneal dialysis (PD) were reviewed. PAD was diagnosed based on the ankle-brachial pressure index (ABI). Demographic and clinical characteristics were analyzed.ResultsPAD had an overall prevalence of 18.2% and was significantly more common in HD patients (21.8%) than in PD patients (4.8%). Advanced age, diabetes mellitus, smoking, low parathyroid hormone level, elevated serum ferritin, elevated serum glucose, and low serum creatinine levels increased the risk for PAD. PAD was independently associated with advanced age, diabetes mellitus, duration of dialysis, low serum creatinine, and hyperlipidemia. PD patients had a significantly lower prevalence of PAD than HD patients, maybe due to their younger age and lower prevalence of diabetes mellitus in this present study.ConclusionsThe prevalence of PAD was greater in the HD group than the PD group. Most of the risk factors for PAD were specific to HD, and no analyzed factor was significantly associated with PAD in PD patients.

【 授权许可】

Unknown   
© Lee et al.; licensee BioMed Central Ltd. 2012. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.