Peripheral artery disease in peritoneal dialysis and hemodialysis patients: single-center retrospective study in Taiwan

BMC Nephrology

Chi-Feng Pan²  Mei-Ching Yeh⁴  Pi-Chu Jen⁴  Sheng-Fang Chiang⁴  Su-Mei Shen⁴  Li-Hua Chou⁴  Chih-Jen Wu³  Chun-Chuan Lee¹ 

[1] Division of Endocrinology and Metabolism, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan;Mackay Medicine, Nursing and Management College, Taipei, Taiwan;College of Medicine, Taipei Medical University, Taipei, Taiwan;Division of Hemodialysis and Peritoneal Dialysis, Department of Nursing, Mackay Memorial Hospital, Taipei, Taiwan

关键词: Peripheral artery disease;    Peritoneal dialysis;    Hemodialysis;    End-stage renal disease;    Cardiovascular disease;    Ankle-brachial pressure index (ABI);   

Others  :  1083111
DOI  :  10.1186/1471-2369-13-100

 received in 2012-05-04, accepted in 2012-08-27,  发布年份 2012

【 摘 要 】

Background

Peripheral artery disease (PAD) is a condition characterized by restricted blood flow to the extremities, and is especially common in the elderly. PAD increases the risk for mortality and morbidity in patients with end-stage renal disease (ESRD), especially those on hemodialysis (HD).

Methods

The records of 484 patients with end-stage renal disease who were on HD or peritoneal dialysis (PD) were reviewed. PAD was diagnosed based on the ankle-brachial pressure index (ABI). Demographic and clinical characteristics were analyzed.

Results

PAD had an overall prevalence of 18.2% and was significantly more common in HD patients (21.8%) than in PD patients (4.8%). Advanced age, diabetes mellitus, smoking, low parathyroid hormone level, elevated serum ferritin, elevated serum glucose, and low serum creatinine levels increased the risk for PAD. PAD was independently associated with advanced age, diabetes mellitus, duration of dialysis, low serum creatinine, and hyperlipidemia. PD patients had a significantly lower prevalence of PAD than HD patients, maybe due to their younger age and lower prevalence of diabetes mellitus in this present study.

Conclusions

The prevalence of PAD was greater in the HD group than the PD group. Most of the risk factors for PAD were specific to HD, and no analyzed factor was significantly associated with PAD in PD patients.

【 授权许可】

   
2012 Lee et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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