Clinical and microbiological characterization of Staphylococcus lugdunensis isolates obtained from clinical specimens in a hospital in China

BMC Microbiology

Research Article

Jing Guo¹  Dingxia Shen²  Huan Wang²  Chaojun Liu²  Kaifei Wang²  Liyan Ye²  Zhongqiang Yan²  Rong Chen² 

[1] Clinical Laboratory, The 261st Hospital of The People’s Liberation Army, Beijing, China;Department of Clinical Microbiology, General Hospital of The People’s Liberation Army, No. 28 Fu Xing Road, Hai Dian District, 100853, Beijing, China;

关键词: Staphylococcus lugdunensis;    Coagulase-negative staphylococci;    Antibiotic resistance;    Pulsed-field gel electrophoresis;    mecA;    ermC;   

DOI  :  10.1186/1471-2180-12-168

 received in 2012-02-21, accepted in 2012-07-17,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundSeveral reports have associated Staphylococcus lugdunensis with the incidence of severe infection in humans; however, the frequency and prevalence of this microorganism and thus the propensity of its antimicrobial drug resistance is unknown in China. The objective of the current study was to determine the prevalence of Staphylococcus lugdunensis among six hundred and seventy non-replicate coagulase negative Staphylococcus (CoNS) isolates collected in a 12-month period from clinical specimens in the General Hospital of the People’s Liberation Army in Beijing, China.ResultsFive (0.7%) of the 670 isolates of CoNS were identified as S. lugdunensis. Whereas three isolates were resistant to erythromycin, clindamycin, and penicillin and carried the ermC gene and a fourth one was resistant to cefoxitin and penicillin and carried the mecA gene, one isolate was not resistant to any of the tested antimicrobials. Pulse field gel electrophoretic analysis did not reveal widespread epidemiological diversity of the different isolates.ConclusionHence, even though S. lugdunensis may be yet unrecognized and undefined in China, it still might be the infrequent cause of infection and profound multi-drug resistance in the same population.

【 授权许可】

Unknown   
© Liu et al.; licensee BioMed Central Ltd. 2012. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.