Clinical characteristics and risk factors for septic shock in patients receiving emergency drainage for acute pyelonephritis with upper urinary tract calculi

BMC Urology

Research Article

Daiki Wada¹  Satoshi Fujimi¹  Ryoichi Imamura²  Yoshiyuki Yamamoto²  Masahiro Hosomi²  Kazutoshi Fujita²  Seiji Yamaguchi²  Shigeaki Nakazawa²  Go Tanigawa²  Takuji Hayashi² 

[1] Department of Emergency, Osaka General Medical Center, Osaka, Japan;Department of Urology, Osaka General Medical Center, Osaka, Japan;

关键词: Septic Shock;    Severe Sepsis;    Poor Performance Status;    Ureteral Obstruction;    Acute Pyelonephritis;   

DOI  :  10.1186/1471-2490-12-4

 received in 2011-09-03, accepted in 2012-03-13,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundAcute pyelonephritis (APN) is a common complication of ureteral obstruction caused by urolithiasis, and it can be lethal if it progresses to septic shock. We investigated the clinical characteristics of patients undergoing emergency drainage and assessed risk factors for septic shock.MethodsA retrospective study was performed of 98 patients (101 events) requiring emergency drainage at our urology department for obstructive APN associated with upper urinary tract calculi from January 2003 to January 2011. Clinical characteristics were summarized, and risk factors for septic shock were assessed by logistic regression analysis.ResultsObjective evidence of sepsis was found in 64 (63.4%) events, and 21 events (20.8%) were categorized as septic shock. Ninety-six patients recovered, but 2 patients died of septic shock. Multivariate analysis revealed that age and the presence of paralysis were independent risk factors for septic shock.ConclusionsAPN associated with upper urinary tract calculi is a severe disease that should be treated with caution, particularly when risk factors are present.

【 授权许可】

Unknown   
© Yamamoto et al; licensee BioMed Central Ltd. 2012. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.