Explaining the increase in coronary heart disease mortality in Syria between 1996 and 2006

BMC Public Health

Research Article

Simon Capewell¹  Martin O'Flaherty¹  Fouad M Fouad²  Radwan AL Ali²  Wasim Maziak³  Fawaz Mzayek⁴  Samer Rastam⁵ 

[1] Department of Public Health and Policy, University of Liverpool, Liverpool, UK;Syrian Centre for Tobacco Studies, Aleppo, Syria;Syrian Centre for Tobacco Studies, Aleppo, Syria;Robert Stempel College of Public Health and Social Work, Florida International University, Miami, FL, USA;Syrian Centre for Tobacco Studies, Aleppo, Syria;School of Public Health, Division of Epidemiology and Biostatistics, University of Memphis, Memphis, TN, USA;Syrian Centre for Tobacco Studies, Aleppo, Syria;Syrian Center for Tobacco Studies Syrian Society against Cancer building, St.Aleppo, Shihan, Syria;

关键词: Coronary heart disease;    Mortality;    Modelling;   

DOI  :  10.1186/1471-2458-12-754

 received in 2012-01-16, accepted in 2012-08-29,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundDespite advances made in treating coronary heart disease (CHD), mortality due to CHD in Syria has been increasing for the past two decades. This study aims to assess CHD mortality trends in Syria between 1996 and 2006 and to investigate the main factors associated with them.MethodsThe IMPACT model was used to analyze CHD mortality trends in Syria based on numbers of CHD patients, utilization of specific treatments, trends in major cardiovascular risk factors in apparently healthy persons and CHD patients. Data sources for the IMPACT model included official statistics, published and unpublished surveys, data from neighboring countries, expert opinions, and randomized trials and meta-analyses.ResultsBetween 1996 and 2006, CHD mortality rate in Syria increased by 64%, which translates into 6370 excess CHD deaths in 2006 as compared to the number expected had the 1996 baseline rate held constant. Using the IMPACT model, it was estimated that increases in cardiovascular risk factors could explain approximately 5140 (81%) of the CHD deaths, while some 2145 deaths were prevented or postponed by medical and surgical treatments for CHD.ConclusionMost of the recent increase in CHD mortality in Syria is attributable to increases in major cardiovascular risk factors. Treatments for CHD were able to prevent about a quarter of excess CHD deaths, despite suboptimal implementation. These findings stress the importance of population-based primary prevention strategies targeting major risk factors for CHD, as well as policies aimed at improving access and adherence to modern treatments of CHD.

【 授权许可】

CC BY   
© Rastam et al.; licensee BioMed Central Ltd. 2012