Validity of the 32-item Hypomania Checklist (HCL-32) in a clinical sample with mood disorders in China

BMC Psychiatry

Research Article

Cheng-mei Yuan¹  Yi-ru Fang¹  Han Rong²  Tie-bang Liu²  Chun-ping Liao²  Hong-jun Peng³  Ling-jiang Li³  Hai-chen Yang⁴  Jules Angst⁵ 

[1] Division of Mood Disorders, Shanghai Mental Health Centre, Shanghai Jiaotong University School of Medicine, 200030, Shanghai, China;Division of Mood Disorders, Shenzhen Mental Health Centre, 518020, Shenzhen, China;Mental Health Institute, the 2nd Xiangya Hospital, Central South University, No. 139 Renmin Zhong Road, 410011, Changsha, China;Mental Health Institute, the 2nd Xiangya Hospital, Central South University, No. 139 Renmin Zhong Road, 410011, Changsha, China;Division of Mood Disorders, Shenzhen Mental Health Centre, 518020, Shenzhen, China;Zurich University Psychiatric Hospital, Switzerland;

关键词: Bipolar Disorder;    Positive Predictive Value;    Negative Predictive Value;    Mood Disorder;    Chinese Version;   

DOI  :  10.1186/1471-244X-11-84

 received in 2010-11-21, accepted in 2011-05-15,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundThe 32-item Hypomania Checklist (HCL-32), a questionnaire for screening bipolar disorders, has been utilised in several countries, but it unclear if the Chinese version of the HCL-32 is valid.MethodsConsecutive patients with bipolar disorders (BP, N = 300) and unipolar major depression (UP, N = 156) completed the Chinese version of the HCL-32. The subjects underwent a structured clinical interview for DSM-IV Axis-I disorders (SCID).ResultsThe eigenvalues for the first three factors in the HCL-32 were calculated as 5.16 (active/elated), 2.72 (risk-taking) and 2.48 (irritable) using factor analysis. Cronbach's alpha for the HCL-32 was calculated to be 0.88. Positive responses to twenty-eight items were significantly more frequent by patients with BP than those with UP, and the other four items (7th, 21st, 25th and 32nd) showed no such trend. Fourteen was the optimal cut-off for discriminating between BP and UP. The HCL-32 distinguished between BP-II and UP, with 13 being the optimal cut-off. A cut-off of 13 yielded a sensitivity of 0.77 and a specificity of 0.62 between BP and UP.ConclusionsThis study demonstrated that the simplified Chinese version of HCL-32 was valid for patients with mood disorders. The optimal cut-off of 13 for distinguishing between BP-II and UP was valid and could be used to improve the sensitivity of screening BP-II patients when the HCL-32 is used in psychiatric settings in China.

【 授权许可】

Unknown   
© Yang et al; licensee BioMed Central Ltd. 2011. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.