ESPECTRA: Searching the Bipolar Spectrum in Eating Disorder patients

BMC Psychiatry

Study Protocol

Ricardo A Moreno¹  Taki A Cordas²  Rodolfo N Campos³  Jules Angst⁴ 

[1] Director of the Mood Disorders Unit (GRUDA). Department and Institute of Psychiatry, Clinicas Hospital, University of Sao Paulo, School of Medicine, Sao Paulo, Brazil;Eating Disorders Unit (AMBULIM) - Department and Institute of Psychiatry, Clinicas Hospital, University of Sao Paulo, School of Medicine, Sao Paulo, Brazil;Researcher of the Mood Disorders Unit (GRUDA). Department and Institute of Psychiatry, Clinicas Hospital, University of Sao Paulo, School of Medicine, Sao Paulo, Brazil;Zurich University Psychiatric Hospital, Zurich, Switzerland;

关键词: Bipolar Disorder;    Eating Disorder;    Anorexia Nervosa;    Eating Disorder;    Mood Disorder;   

DOI  :  10.1186/1471-244X-11-59

 received in 2010-10-08, accepted in 2011-04-14,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundBipolar Disorder (BD) is a chronic, recurrent and highly prevalent illness. Despite the need for correct diagnosis to allow proper treatment, studies have shown that reaching a diagnosis can take up to ten years due to the lack of recognition of the broader presentations of BD. Frequent comorbidities with other psychiatric disorders are a major cause of misdiagnosis and warrant thorough evaluation.Methods/DesignESPECTRA (Occurrence of Bipolar Spectrum Disorders in Eating Disorder Patients) is a single-site cross-sectional study involving a comparison group, designed to evaluate the prevalence of bipolar spectrum in an eating disorder sample. Women aged 18-45 years will be evaluated using the SCID-P and Zurich criteria for diagnosis and the HAM-D, YOUNG, SCI-MOODS, HCL-32, BIS-11, BSQ, WHOQoL and EAS instruments for rating symptoms and measuring clinical correlates.DiscussionThe classificatory systems in psychiatry are based on categorical models that have been criticized for simplifying the diagnosis and leading to an increase in comorbidities. Some dimensional approaches have been proposed aimed at improving the validity and reliability of psychiatric disorder assessments, especially in conditions with high rates of comorbidity such as BD and Eating Disorder (ED). The Bipolar Spectrum (BS) remains under-recognized in clinical practice and its definition is not well established in current diagnostic guidelines. Broader evaluation of psychiatric disorders combining categorical and dimensional views could contribute to a more realistic understanding of comorbidities and help toward establishing a prognosis.

【 授权许可】

CC BY   
© Campos et al; licensee BioMed Central Ltd. 2011