Total parathyroidectomy with trace amounts of parathyroid tissue autotransplantation as the treatment of choice for secondary hyperparathyroidism: a single-center experience

BMC Surgery

Research Article

Yanming Ge¹  Qingqing He²  Songjian Duan²  Jian Zhu²  Dayong Zhuang²  Zhen Lv²  Luming Zheng²  Lei Cao²  Peng Zhou²  Yanning Li²  Ziyi Fan² 

[1] Blood Purification Center, Jinan Military General Hospital of PLA, 250031, Jinan, People's Republic of China;Department of Thyroid and Breast Surgery, Jinan Military General Hospital of PLA, No.25 Shifan Road, 250031, Jinan, People's Republic of China;

关键词: Secondary hyperparathyroidism;    Chronic renal failure;    Total parathyroidectomy;    Parathyroid hormone;    Autotransplantation;   

DOI  :  10.1186/1471-2482-14-26

 received in 2013-04-27, accepted in 2014-04-25,  发布年份 2014

来源: Springer

【 摘 要 】

BackgroundThe aim of the study was to evaluate total parathyroidectomy with trace amounts of parathyroid tissue (30 mg) as a surgical option in secondary hyperparathyroidism (sHPT) treatment.MethodsFrom January 2008 to March 2012, 47 patients underwent parathyroidectomy. Comparisons of demographic data, symptoms, and preoperative or postoperative biochemistry were made between total parathyroidectomy with trace amounts of parathyroid tissue autotransplantation group and total parathyroidectomy group.ResultsOut of 47 cases, 45 had successful operation. 187 parathyroid glands identified at the initial operation were reported in 47 patients. 43 patients had been diagnosed with parathyroid hyperplasia, and 4 patients had a benign adenoma. After operation, pruritus, bone pain and muscle weakness disappeared, also serum PTH and serum phosphate were declined markedly as well. After discharge, two patients (in total parathyroidectomy group) were readmitted because of postoperative hypoparathyroidism. Graft-dependent recurrence was not observed in an average follow-up of 42 months.ConclusionsTotal parathyroidectomy with sternocleidomastoid muscle trace amounts of parathyroid tissue autotransplantation is considered to be a feasible, safe and effective surgical option for the patients with sHPT.

【 授权许可】

CC BY   
© He et al.; licensee BioMed Central Ltd. 2014