Prevalence of diabetes and predictions of its risks using anthropometric measures in southwest rural areas of China

BMC Public Health

Research Article

Linghu Cai¹  Jiping Zhou¹  Xiaoming Zhu²  Weiwei Zhao²  Xiaolong Zhao²  Yiming Li²  Songwu Li³  Yonghui Shu³  Jinhui Li³  Minghui Yang³  Hengsheng Zhang³ 

[1] Center for Disease Control and Prevention of Songming Country, Yunnan Province, China;Department of Endocrinology & Metabolism, Huashan Hospital, Medical College Fudan University, Shanghai, China;Department of Internal Medicine, People’s Hospital, Songming County, Yunnan Province, China;

关键词: Obesity;    Waist-to-height ratio;    Body mass index;    Waist hip ratio;    Diabetes type 2;   

DOI  :  10.1186/1471-2458-12-821

 received in 2012-03-27, accepted in 2012-09-14,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundTo examine the prevalence of diabetes and prediabetes in Songming county, Yunnan province, South-west China and examine influences of anthropometric indicators on diabetic risk.MethodsThis study was a population based cross-sectional study of 1031 subjects in Songming County aged 30 years and older. Age-standardization was performed by using the 2010 Songming population as the standard population. After an overnight fasting, participants underwent an oral glucose tolerance test (OGTT), and venous blood glucose levels were measured to identify diabetes and prediabetes. Physicians completed questionnaires and blood pressure measurements; trained nurses measured anthropometric variables. Age-adjusted logistic regression models were used to assess the association between anthropometric variables and diabetes.ResultsTotal prevalences of diabetes and prediabetes were 10.0% and 11.6%, respectively. In women, prevalence of diabetes and prediabetes significantly increased with body mass index (BMI),waist hip ratio (WHR), and waist-to-height ratio (WHtR). But in men, prevalence of diabetes and prediabetes only significantly increased with WHR and WHtR. Compared to 1st WHR tertile in women, there was a nearly tenfold increase in the risk of diabetes with 3rd WHR tertile (OR 10.50, 95% CI 3.95-27.86). Men with 3rd BMI tertile had 4.8-fold risk of getting diabetes compared to men with 1st WHtR tertile (OR 4.79, 95% CI 1.88-12.26). Only WHtR had significantly higher receiver operating characteristic (ROC) area than BMI in total men (0.668 vs. 0.561, p < 0.05). And in total women, only WHR had significantly higher ROC area than BMI (0.723 vs. 0.628, p < 0.05). In the partial correlation analysis controlling for waist circumference, only WHR had significant correlation with fasting plasma glucose (r = 0.132, p = 0.002) and 2-h plasma glucose (r = 0.162, p = 0.000) in women, and WHtR had a much stronger association with both fasting plasma glucose (r = 0.305, P = 0.000) and 2 h plasma glucose (r = 0.303, P = 0.000) than WHR in men.ConclusionHigh prevalence of diabetes and prediabetes were found in this underdeveloped region. About half of total subjects with diabetes were undiagnosed. The association of obesity indices and diabetic risk factors varied with gender. The strongest predictors of diabetes were WHR for the female subgroup and WHtR for the male subgroup.

【 授权许可】

CC BY   
© Zhao et al.; licensee BioMed Central Ltd. 2012