Chronic obstructive pulmonary disease, bronchial asthma and allergic rhinitis in the adult population within the Commonwealth of Independent States: rationale and design of the CORE study

BMC Pulmonary Medicine

Research Article

Marcelo Horacio S. Pereira¹  Luqman Tariq²  Janina Makarova³  Alexander Markov⁴  Maryna Moibenko⁴  Averyan Vasylyev⁴  Yuriy Feshchenko⁵  Liudmyla Iashyna⁵  Maryna Polianska⁵  Olga Gyrina⁶  Eljan Mammadbayov⁷  Irada Akhundova⁷  Damilya Nugmanova⁸ 

[1] Department of Internal Medicine, State University of Rio de Janeiro (UERJ), Rio de Janeiro, Brazil;GlaxoSmithKline, Dubai, UAE;GlaxoSmithKline, GSK Russia, Business Park “Krylatsky Hills”, 17, Krylatskaya Street, Building 3 (“Air”), 121614, Moscow, Russia;GlaxoSmithKline, Kiev, Ukraine;National Institute of Phthisiology and Pulmonology F.G. Yanovsky of NAMS, Kiev, Ukraine;National Medical University n.a. O.O. Bogomolets, Kiev, Ukraine;Scientific Research Institute of Lung Diseases, Baku, Azerbaijan;Semey State Medical University, Almaty, Kazakhstan;

关键词: Chronic respiratory diseases;    COPD;    Bronchial asthma;    Allergic rhinitis;    Prevalence;    Study design;    Risk factors;    Ukraine;    Kazakhstan;    Azerbaijan;   

DOI  :  10.1186/s12890-017-0471-x

 received in 2017-02-17, accepted in 2017-06-29,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundMain treatable Chronic Respiratory Diseases (CRDs) like Chronic Obstructive Pulmonary Disease (COPD), Bronchial Asthma (BA) and Allergic Rhinitis (AR) are underdiagnosed and undertreated worldwide. CORE study was aimed to assess the point prevalence of COPD, BA and AR in the adult population of major cities of Commonwealth of Independent States (CIS) countries – Azerbaijan, Kazakhstan, and Ukraine based on study questionnaires and/or spirometry, and to document risk factors, characterize the COPD, BA and AR population to provide a clearer “epidemiological data”.MethodsA descriptive, cross-sectional, population-based epidemiological study conducted from 2013 to 2015 with two-stage cluster geographical randomization. Interviewers conducted face-to-face visits at respondent’s household after informed consent and eligibility assessment including interviews, anthropometry, spirometry (with bronchodilator test) and completion of disease-specific questionnaires.ResultsTwo thousand eight hundred forty-two respondents (Ukraine: 964 from Ukraine; 945 from Kazakhstan; 933 Azerbaijan) were enrolled. Mean age was 40–42 years and males were 37%–42% across three countries. In Kazakhstan 62.8% were Asians, but in Ukraine and in Azerbaijan 99.7% and 100.0%, respectively, were Caucasians. Manual labourers constituted 40.5% in Ukraine, 22.8% in Kazakhstan and 22.0% in Azerbaijan, while office workers were 16.1%, 31.6% and 36.8% respectively. 51.3% respondents in Ukraine, 64.9% in Kazakhstan and 69.7% in Azerbaijan were married.ConclusionCORE study collected information that can be supportive for health policy decision makers in allocating healthcare resources in order to improve diagnosis and management of CRDs. The detailed findings will be described in future publications.Trial registrationStudy Protocol Summary is disclosed at GlaxoSmithKline Clinical Study Register on Jun 06, 2013, study ID 116757.

【 授权许可】

CC BY   
© The Author(s). 2017