Chronic obstructive pulmonary disease, bronchial asthma and allergic rhinitis in the adult population within the Commonwealth of Independent States: rationale and design of the CORE study

BMC Pulmonary Medicine

Marcelo Horacio S. Pereira¹  Alexander Markov²  Luqman Tariq²  Janina Makarova²  Averyan Vasylyev²  Maryna Moibenko²  Maryna Polianska³  Yuriy Feshchenko³  Liudmyla Iashyna³  Olga Gyrina⁴  Eljan Mammadbayov⁵  Irada Akhundova⁵  Damilya Nugmanova⁶ 

[1] Department of Internal Medicine, State University of Rio de Janeiro (UERJ);GlaxoSmithKline;National Institute of Phthisiology and Pulmonology F.G. Yanovsky of NAMS;National Medical University n.a. O.O. Bogomolets;Scientific Research Institute of Lung Diseases;Semey State Medical University;

关键词: Chronic respiratory diseases;    COPD;    Bronchial asthma;    Allergic rhinitis;    Prevalence;    Study design;   

DOI  :  10.1186/s12890-017-0471-x

来源: DOAJ

【 摘 要 】

Abstract Background Main treatable Chronic Respiratory Diseases (CRDs) like Chronic Obstructive Pulmonary Disease (COPD), Bronchial Asthma (BA) and Allergic Rhinitis (AR) are underdiagnosed and undertreated worldwide. CORE study was aimed to assess the point prevalence of COPD, BA and AR in the adult population of major cities of Commonwealth of Independent States (CIS) countries – Azerbaijan, Kazakhstan, and Ukraine based on study questionnaires and/or spirometry, and to document risk factors, characterize the COPD, BA and AR population to provide a clearer “epidemiological data”. Methods A descriptive, cross-sectional, population-based epidemiological study conducted from 2013 to 2015 with two-stage cluster geographical randomization. Interviewers conducted face-to-face visits at respondent’s household after informed consent and eligibility assessment including interviews, anthropometry, spirometry (with bronchodilator test) and completion of disease-specific questionnaires. Results Two thousand eight hundred forty-two respondents (Ukraine: 964 from Ukraine; 945 from Kazakhstan; 933 Azerbaijan) were enrolled. Mean age was 40–42 years and males were 37%–42% across three countries. In Kazakhstan 62.8% were Asians, but in Ukraine and in Azerbaijan 99.7% and 100.0%, respectively, were Caucasians. Manual labourers constituted 40.5% in Ukraine, 22.8% in Kazakhstan and 22.0% in Azerbaijan, while office workers were 16.1%, 31.6% and 36.8% respectively. 51.3% respondents in Ukraine, 64.9% in Kazakhstan and 69.7% in Azerbaijan were married. Conclusion CORE study collected information that can be supportive for health policy decision makers in allocating healthcare resources in order to improve diagnosis and management of CRDs. The detailed findings will be described in future publications. Trial registration Study Protocol Summary is disclosed at GlaxoSmithKline Clinical Study Register on Jun 06, 2013, study ID 116757 .

【 授权许可】

Unknown