Effect of negative emotions evoked by light, noise and taste on trigeminal thermal sensitivity

The Journal of Headache and Pain

Research Article

Kelun Wang¹  Qiu-Fei Xie²  Guangju Yang²  Lene Baad-Hansen³  Peter Svensson⁴ 

[1] Center for Sensory-Motor Interaction (SMI), Department of Health Science and Technology, Aalborg University, Aalborg, Denmark;Department of Prosthodontics and Center for Oral Functional Diagnosis, Treatment and Research, Peking University School and hospital of Stomatology, Zhongguancun Nandajie 22, 100081, Beijing, China;Section of Clinical Oral Physiology, Department of Dentistry, Aarhus University, Aarhus, Denmark;Section of Clinical Oral Physiology, Department of Dentistry, Aarhus University, Aarhus, Denmark;Department of Dental Medicine, Karolinska Institute, Huddinge, Sweden;

关键词: Quantitative sensory testing;    Affective state;    Thermal sensitivity;    Light;    Noise;    Taste;   

DOI  :  10.1186/1129-2377-15-71

 received in 2014-08-28, accepted in 2014-10-28,  发布年份 2014

来源: Springer

【 摘 要 】

BackgroundPatients with migraine often have impaired somatosensory function and experience headache attacks triggered by exogenous stimulus, such as light, sound or taste. This study aimed to assess the influence of three controlled conditioning stimuli (visual, auditory and gustatory stimuli and combined stimuli) on affective state and thermal sensitivity in healthy human participants.MethodsAll participants attended four experimental sessions with visual, auditory and gustatory conditioning stimuli and combination of all stimuli, in a randomized sequence. In each session, the somatosensory sensitivity was tested in the perioral region with use of thermal stimuli with and without the conditioning stimuli. Positive and Negative Affect States (PANAS) were assessed before and after the tests. Subject based ratings of the conditioning and test stimuli in addition to skin temperature and heart rate as indicators of arousal responses were collected in real time during the tests.ResultsThe three conditioning stimuli all induced significant increases in negative PANAS scores (paired t-test, P ≤0.016). Compared with baseline, the increases were in a near dose-dependent manner during visual and auditory conditioning stimulation. No significant effects of any single conditioning stimuli were observed on trigeminal thermal sensitivity (P ≥0.051) or arousal parameters (P ≥0.057). The effects of combined conditioning stimuli on subjective ratings (P ≤0.038) and negative affect (P = 0.011) were stronger than those of single stimuli.ConclusionsAll three conditioning stimuli provided a simple way to evoke a negative affective state without physical arousal or influence on trigeminal thermal sensitivity. Multisensory conditioning had stronger effects but also failed to modulate thermal sensitivity, suggesting that so-called exogenous trigger stimuli e.g. bright light, noise, unpleasant taste in patients with migraine may require a predisposed or sensitized nervous system.

【 授权许可】

Unknown   
© Yang et al.; licensee Springer. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.