COVID-19 associated Mucormycosis among ICU patients: risk factors, control, and challenges

AMB Express

Mini-Review

Israa M. S. Al-Kadmy¹  Helal F. Hetta²  Yasmin N. Ramadan³  Esraa R. Shady⁴  Ramadan Yahia⁴  Fatma Y. Ahmed⁵  Hala Rady Ahmed⁵  Mohamed Ramadan⁵  Rehab Mahmoud Abd El-Baky⁶ 

[1] Branch of Biotechnology, Department of Biology, College of Science, Mustansiriyah University, POX 10244, Baghdad, Iraq;Department of Medical Microbiology and Immunology, Faculty of Medicine, Assiut University, 71515, Assiut, Egypt;Department of Microbiology and Immunology, Faculty of Pharmacy, Assiut University, 71515, Assiut, Egypt;Department of Microbiology and Immunology, Faculty of Pharmacy, Deraya University, 11566, Minia, Egypt;Department of Microbiology and Immunology, Faculty of Pharmacy, Minia University, 61519, Minia, Egypt;Department of Microbiology and Immunology, Faculty of Pharmacy, Minia University, 61519, Minia, Egypt;Department of Microbiology and Immunology, Faculty of Pharmacy, Deraya University, 11566, Minia, Egypt;

关键词: SARS-CoV-2;    Risk factors;    Opportunistic pathogens;    Mucormycosis;    Control measures;   

DOI  :  10.1186/s13568-023-01599-8

 received in 2023-06-29, accepted in 2023-08-24,  发布年份 2023

来源: Springer

【 摘 要 】

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic is still difficult to be controlled. The spread of this virus and the emergence of new variants are considered a great challenge worldwide. Disturbance in infection control guidelines implementation, use of steroids, antibiotics, hospital crowdedness, and repeated use of oxygen masks during the management of critically ill COVID-19 patients lead to an increase in the rate of opportunistic infections. So, patients need to fight both the virus with its different variants and opportunistic pathogens including bacteria and fungi especially patients with diabetes mellitus, malignancy, or those who undergo hemodialysis and receive deferoxamine. During the pandemic, many cases of Mucormycosis associated with COVID-19 infection were observed in many countries. In this review, we discuss risk factors that increase the chance of infection by opportunistic pathogens, especially fungal pathogens, recent challenges, and control measures.

【 授权许可】

CC BY   
© Springer-Verlag GmbH Germany, part of Springer Nature 2023

【 图 表 】

Fig. 7

Fig. 2

Fig. 5