What we talk about when we talk about COVID-19 vaccination campaign impact: a narrative review

Frontiers in Public Health

Public Health

Otavio T. Ranzani¹  Lucas G. Maddalena²  Paula M. Maçaira²  Fernanda A. Baião²  Silvio Hamacher²  Igor T. Peres²  Horácio N. Hastenreiter Filho³  Fernando A. Bozza⁴ 

[1] Barcelona Institute for Global Health, Barcelona, Spain;Pulmonary Division, Heart Institute, Faculty of Medicine, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil;Department of Industrial Engineering, Pontifical Catholic University of Rio de Janeiro, Rio de Janeiro, Brazil;Department of Industrial Engineering, Pontifical Catholic University of Rio de Janeiro, Rio de Janeiro, Brazil;School of Management, Federal University of Bahia, Salvador, Brazil;National Institute of Infectious Disease Evandro Chagas, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil;D'Or Institute for Research and Education, Rio de Janeiro, Brazil;

关键词: vaccine impact;    narrative review;    COVID-19;    vaccination campaign;    populational studies;   

DOI  :  10.3389/fpubh.2023.1126461

 received in 2022-12-17, accepted in 2023-04-06,  发布年份 2023

来源: Frontiers

【 摘 要 】

BackgroundThe lack of precise definitions and terminological consensus about the impact studies of COVID-19 vaccination leads to confusing statements from the scientific community about what a vaccination impact study is.ObjectiveThe present work presents a narrative review, describing and discussing COVID-19 vaccination impact studies, mapping their relevant characteristics, such as study design, approaches and outcome variables, while analyzing their similarities, distinctions, and main insights.MethodsThe articles screening, regarding title, abstract, and full-text reading, included papers addressing perspectives about the impact of vaccines on population outcomes. The screening process included articles published before June 10, 2022, based on the initial papers’ relevance to this study’s research topics. The main inclusion criteria were data analyses and study designs based on statistical modelling or comparison of pre- and post-vaccination population.ResultsThe review included 18 studies evaluating the vaccine impact in a total of 48 countries, including 32 high-income countries (United States, Israel, and 30 Western European countries) and 16 low- and middle-income countries (Brazil, Colombia, and 14 Eastern European countries). We summarize the main characteristics of the vaccination impact studies analyzed in this narrative review.ConclusionAlthough all studies claim to address the impact of a vaccination program, they differ significantly in their objectives since they adopt different definitions of impact, methodologies, and outcome variables. These and other differences are related to distinct data sources, designs, analysis methods, models, and approaches.

【 授权许可】

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Copyright © 2023 Hastenreiter Filho, Peres, Maddalena, Baião, Ranzani, Hamacher, Maçaira and Bozza.