Implications of the medication regimen complexity index score on hospital readmissions in elderly patients with heart failure: a retrospective cohort study

BMC Geriatrics

Research

Salah Elbdri¹  Afif Ahmed²  Moza Al Hail²  Shaikha Alnaimi²  Abdulqadir J. Nashwan³  Shiema Ahmed⁴  Asmaa Abdelbary⁵  Richard Galvez⁶  Sara Al Balushi⁶  Rasha Kaddoura⁶ 

[1] Cardiology Department, Heart Hospital, Hamad Medical Corporation, Doha, Qatar;Corporate Pharmacy Department, Hamad Medical Corporation, Doha, Qatar;Nursing Department, Hamad Medical Corporation, P.O. Box 3050, Doha, Qatar;Pharmacy Department, Communicable Disease Center, Hamad Medical Corporation, Doha, Qatar;Pharmacy Department, Community and Home Health Services, Hamad Medical Corporation, Doha, Qatar;Pharmacy Department, Heart Hospital, Hamad Medical Corporation, Doha, Qatar;

关键词: Elderly;    Heart failure;    Medication regimen complexity;    Polypharmacy;   

DOI  :  10.1186/s12877-023-04062-2

 received in 2023-02-27, accepted in 2023-05-23,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundThe likelihood of elderly patients with heart failure (HF) being readmitted to the hospital is higher if they have a higher medication regimen complexity index (MRCI) compared to those with a lower MRCI. The objective of this study was to investigate whether there is a correlation between the MRCI score and the frequency of hospital readmissions (30-day, 90-day, and 1-year) among elderly patients with HF.MethodsIn this single-center retrospective cohort study, MRCI scores were calculated using a well-established tool. Patients were categorized into high (≥ 15) or low (< 15) MRCI score groups. The primary outcome examined the association between MRCI scores and 30-day hospital readmission rates. Secondary outcomes included the relationships between MRCI scores and 90-day readmission, one-year readmission, and mortality rates. Multivariate logistic regression was employed to assess the 30- and 90-day readmission rates, while Kaplan-Meier analysis was utilized to plot mortality.ResultsA total of 150 patients were included. The mean MRCI score for all patients was 33.43. 90% of patients had a high score. There was no link between a high MCRI score and a high 30-day readmission rate (OR 1.02; 95% CI 0.99–1.05; p < 0.13). A high MCRI score was associated with an initial significant increase in the 90-day readmission rate (odd ratio, 1.03; 95% CI, 1.00-1.07; p < 0.022), but not after adjusting for independent factors (odd ratio, 0.99; 95% CI, 0.95–1.03; p < 0.487). There was no significant difference between high and low MRCI scores in their one-year readmission rate.ConclusionThe study’s results indicate that there is no correlation between a higher MRCI score and the rates of hospital readmission or mortality among elderly patients with HF. Therefore, it can be concluded that the medication regimen complexity index does not appear to be a significant predictor of hospital readmission or mortality in this population.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

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