Dietary fiber during gestation improves lactational feed intake of sows by modulating gut microbiota

Journal of Animal Science and Biotechnology

Research

Xilun Zhao¹  Lianqiang Che¹  Yong Zhuo¹  Lun Hua¹  Ke Wang¹  Shuang Li¹  Hao Liu¹  Bin Feng¹  Xuemei Jiang¹  Liansu Huang¹  Jian Li¹  Yan Lin¹  Jiaqi He¹  Shengyu Xu¹  Zhengfeng Fang¹  Jie Zheng¹  Yingyan Huang¹  De Wu¹ 

[1] Key Laboratory for Animal Disease-Resistance Nutrition of China Ministry of Education, Institute of Animal Nutrition, Sichuan Agricultural University, No. 211, Huimin Road, Wenjiang District, 611130, Chengdu, Sichuan, People’s Republic of China;

关键词: Dietary fiber;    Escherichia-Shigella;    Feed intake;    Lactobacillus;    Sow;   

DOI  :  10.1186/s40104-023-00870-z

 received in 2022-11-21, accepted in 2023-03-14,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundThe feed intake of sows during lactation is often lower than their needs. High-fiber feed is usually used during gestation to increase the voluntary feed intake of sows during lactation. However, the mechanism underlying the effect of bulky diets on the appetites of sows during lactation have not been fully clarified. The current study was conducted to determine whether a high-fiber diet during gestation improves lactational feed intake (LFI) of sows by modulating gut microbiota.MethodsWe selected an appropriate high-fiber diet during gestation and utilized the fecal microbial transplantation (FMT) method to conduct research on the role of the gut microbiota in feed intake regulation of sows during lactation, as follows: high-fiber (HF) diet during gestation (n = 23), low-fiber (LF) diet during gestation (n = 23), and low-fiber diet + HF-FMT (LFM) during gestation (n = 23).ResultsCompared with the LF, sows in the HF and LFM groups had a higher LFI, while the sows also had higher peptide tyrosine tyrosine and glucagon-like peptide 1 on d 110 of gestation (G110 d). The litter weight gain of piglets during lactation and weaning weight of piglets from LFM group were higher than LF group. Sows given a HF diet had lower Proteobacteria, especially Escherichia-Shigella, on G110 d and higher Lactobacillus, especially Lactobacillus_mucosae_LM1 and Lactobacillus_amylovorus, on d 7 of lactation (L7 d). The abundance of Escherichia-Shigella was reduced by HF-FMT in numerically compared with the LF. In addition, HF and HF-FMT both decreased the perinatal concentrations of proinflammatory factors, such as endotoxin (ET), lipocalin-2 (LCN-2), tumor necrosis factor-α (TNF-α), and interleukin-1β (IL-1β). The concentration of ET and LCN-2 and the abundance of Proteobacteria and Escherichia-Shigella were negatively correlated with the LFI of sows.ConclusionThe high abundance of Proteobacteria, especially Escherichia-Shigella of LF sows in late gestation, led to increased endotoxin levels, which result in inflammatory responses and adverse effects on the LFI of sows. Adding HF during gestation reverses this process by increasing the abundance of Lactobacillus, especially Lactobacillus_mucosae_LM1 and Lactobacillus_amylovorus.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

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