Neutrophil extracellular traps in acute coronary syndrome

Journal of Inflammation

Review

Yongnan Li¹  Xiangyang Wu¹  Xue Han¹  Yawen Wu²  Shilin Wei³ 

[1] Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou University, No. 80 Cuiyingmen, Chengguan District, 730030, Lanzhou, China;Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou University, No. 80 Cuiyingmen, Chengguan District, 730030, Lanzhou, China;Second Clinical Medical College, Lanzhou University, Lanzhou, China;Department of Thoracic Surgery, Lanzhou University Second Hospital, Lanzhou University, Lanzhou, China;

关键词: Neutrophil extracellular traps;    Acute coronary syndrome;    Atherosclerosis;    Myocardial infarction;    Heart failure;   

DOI  :  10.1186/s12950-023-00344-z

 received in 2023-02-06, accepted in 2023-05-04,  发布年份 2023

来源: Springer

【 摘 要 】

Acute coronary syndrome (ACS) is a group of clinical syndromes caused by acute myocardial ischemia, which can cause heart failure, arrhythmia and even sudden death. It is the major cause of disability and death worldwide. Neutrophil extracellular traps (NETs) are reticular structures released by neutrophils activation and have various biological functions. NETs are closely related to the occurrence and development of ACS and also the subsequent damage after myocardial infarction. The mechanisms are complex and interdependent on various pathways, which require further exploration. This article reviewed the role and mechanism of NETs in ACS, thereby providing a valuable reference for the diagnosis and clinical treatment of ACS.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

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