Liriodendrin, ameliorates hypertension by calcium channel blockade and enhancing enos expression in wistar rats

Cardiometry

article

Anjali B. Tajanpure¹  Vandana S. Nade¹  Laxman A. Kawale¹ 

[1] Savitribai Phule Pune University India

关键词: DOCA;    Hypertension;    Endothelial dysfunction;    Oxidative stress;    Liriodendrin;   

DOI  :  10.18137/cardiometry.2021.20.4759

学科分类：环境科学（综合）

来源: Russian New University

【 摘 要 】

Hypertension is found to be the prime cause of death worldwide in spite of a number of available treatments which suggests that there is a need of discovering new lead molecules that would be more effective to treat cardiovascular disease (CVD). Liriodendrin, the lignan phytoconstituent possesses potential pharmacological effects. Literature survey suggests that liriodendrin could be effective in mitigating hypertension considering its structural similarity with reported cardiovascular protective drugs. Hence liriodendrin is investigated to reveal its mechanism of actions to support its antihypertensive property.

【 授权许可】

CC BY