Association of fibrinogen with HbA1C in diabetic foot ulcer

1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara

Pase, M.A.^1 ; Gatot, D.^2 ; Lindarto, D.^1

Division of Endocrinology, Metabolism and Diabetes, Internal Medicine Department, Medical Faculty, Universitas Sumatera Utara, Indonesia^1

Division of Hematology and Medical-Oncologic, Internal Medicine Department, Medical Faculty, Universitas Sumatera Utara, Indonesia^2

关键词: Ankle-brachial indices;    Diabetic foot ulcer;    Diabetic patient;    Endothelial dysfunction;    General hospitals;    Glycemic control;    Serum levels;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012165/pdf
DOI  :  10.1088/1755-1315/125/1/012165

来源: IOP

【 摘 要 】

Fibrinogen is one of the inflammatory markers of vascular changes and endothelial dysfunction in diabetic patients. The aim of this study to associate serum fibrinogen levels with HbA1C in diabetic foot ulcer (DFU). This study was cross-sectional and retrospective in DFU patients from January to July 2017 in Haji Adam Malik Central General Hospital. The patients enrolled in the study were T2DM with DFU as a complication. The grading of DFU was evaluated according to the Wagner's Classification. Serum fibrinogen level, HbA1C and ankle-brachial index (ABI) were carried out directly in the patients. Fibrinogen serum levels were found significantly with HbA1C (P=0.001, r=0.387) and ABI (P=0.008, r=-0.454). Fibrinogen serum levels in DFU patients were positively correlated with HbA1C and significantly higher in patients with poor glycemic control.