Musculoskeletal Disorders in Chronic Obstructive Airway Diseases: A Neglected Clinical Entity

Mediterranean Journal of Rheumatology

article

C. Mohan Rao¹  Pratima Singh¹  Debashis Maikap²  Prasanta Padhan² 

[1] Department of Pulmonary Medicine, Kalinga Institute of Medical Sciences, KIIT University;Department of Clinical Immunology and Rheumatology, Kalinga Institute of Medical Sciences, KIIT University

关键词: COPD;    Skeletal muscle;    osteoporosis;   

DOI  :  10.31138/mjr.32.2.118

学科分类：社会科学、人文和艺术（综合）

来源: PCO Convin S.A.

【 摘 要 】

Chronic obstructive pulmonary disease (COPD) is a lung disease that can affect various extra-pulmonary organs; one being the musculoskeletal system. Skeletal muscle dysfunction and osteoporosis are two important musculoskeletal disorders that have an impact on the quality of life in COPD patients in terms of morbidity and mortality. Treatment related adverse effects of COPD such as steroid-induced myopathy and osteoporosis are well recognised. Other comorbidities like sarcopenia, cardiovascular disease, metabolic diseases (diabetes mellitus, obesity, and thyroid diseases), chronic kidney disease, sleep apnoea, anaemia, and depression are also noted, which can contribute to impaired health status, increased healthcare utilisation, and even mortality. As well, it has been shown that autoimmunity and autoimmune rheumatic diseases (AIRDs) are linked to COPD. In this mini-review, we intend to give an overview of different types of musculoskeletal disorders associated with COPD.

【 授权许可】

CC BY-NC