Clinical relevance of IL-6 and lactate levels within 24 hours of ICU admission of COVID–19 patients in predicting mortality rate

Anaesthesia, Pain & Intensive Care

article

Harles Sitompul¹  Andy Nugroho¹  Sugeng Budi Santoso¹  Septian Adi Permana¹  Paramita Putri Hapsari² 

[1] Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Sebelas Maret University – Dr. Moewardi General Hospital, Surakarta, Central Java;Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Sebelas Maret University– Dr. Moewardi General Hospital, Surakarta, Central Java

关键词: IL-6;    Lactate;    ICU;    COVID-19;    SARS-CoV-2;   

DOI  :  10.35975/apic.v26i5.2032

学科分类：社会科学、人文和艺术（综合）

来源: THK

【 摘 要 】

Background & objective: Patients with COVID-19 have Acute Respiratory Distress Syndrome (ARDS) which progresses to lung edema and disorders of the liver, kidneys and heart associated with cytokine storms, which are the body's immune response to SARS-CoV-2. SARS-CoV-2 patients showed clinical neutrophilia, increased D-Dimer and increased IL-6. In addition, increased lactate dehydrogenase and increased aminotransferase are often found. This study aimed to analyze the clinical relevance of increased IL-6 and lactate in the first 24 hours of ICU-admission of COVID-19 patients in predicting mortality rate.

【 授权许可】

CC BY-NC