Functional-drink rich in antioxidant cardamom-rhizome (Amomum cardamomum willd) suppresses inflammation and improves lipid profile

International Symposium on Food and Agro-biodiversity 2017

农业科学;生物科学

Winarsi, H.^1 ; Susilowati, S.S.^2

Faculty of Health Sciences, Department of Nutrition Science, University of Jenderal Soedirman, Indonesia^1

Faculty of Health Sciences, Department of Pharmacy, University of Jenderal Soedirman, Purwokerto, Central Java, Indonesia^2

关键词: Cardamom rhizome;    functional drink;    Hypercholesterolemia;    Hypertriglyceridemia;    IL-6;    Lipid profile;    Research subjects;    Total cholesterols;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/102/1/012048/pdf
DOI  :  10.1088/1755-1315/102/1/012048

来源: IOP

【 摘 要 】

The aim of this research was to know the effect of functional drink rich in antioxidant cardamom rhizome (Fd-Carrhi) on level of IL-6, C-RP, and lipid profile of atherosclerotic. A total of 30 women with atherosclerosis, age 40-65 years old, hypertension, hypercholesterolemia, hypertriglyceridemia, lived in Purwokerto, Banyumas, Central Java, Indonesia, and were willing to sign informed consent, recruited as research subjects. They consumed simvastatin from doctors, divided by 3 groups of 10 people each. Group I, given Fd-Carrhi; II, placebo; and III, only simvastatin, for 2 months. As many as 100 ml of Fd-Carrhi or placebo were given every morning. Blood samples were taken 3 times, 1 ml, at baseline, 1 and 2 months after intervention. Blood plasma was determined levels of IL-6, C-RP, as well as total cholesterol (total-c), triglycerides (TG), LDL-c, and HDL-c. Result showed Fd-Carrhi versus placebo significantly decreased plasma level of IL-6, C-RP, total-c, and LDL-c, and otherwise increased HDL-c, but no differences were seen in TG. The findings clearly support Fd-Carrhi inhibit the development of atherosclerosis towards cardiovascular heart diseases (CHD) by suppressing IL-6 and CRP levels, and improving lipid profile.