期刊论文详细信息
PeerJ | |
Effects of stigmata maydis on the methicillin resistant Staphylococus aureus biofilm formation | |
article | |
Fei Shang1  Long Li1  Lumin Yu1  Jingtian Ni1  Xiaolin Chen1  Ting Xue1  | |
[1]School of Life Sciences, Anhui Agricultural University | |
关键词: MRSA; Bovine mastitis; Biofilm; Vancomycin; Stigmata maydis; | |
DOI : 10.7717/peerj.6461 | |
学科分类:社会科学、人文和艺术(综合) | |
来源: Inra | |
【 摘 要 】
Background Mastitis is an inflammatory reaction of the mammary gland tissue, which causes huge losses to dairy farms throughout the world. Staphylococcus aureus is the most frequent agent associated with this disease. Staphylococcus aureus isolates, which have the ability to form biofilms, usually lead to chronic mastitis in dairy cows. Moreover, methicillin resistance of the bacteria further complicates the treatment of this disease. Stigmata maydis (corn silk), a traditional Chinese medicine, possess many biological activities. Methods In this study, we performed antibacterial activity assays, biofilm formation assays and real-time reverse transcription PCR experiments to investigate the effect of stigmata maydis (corn silk) on biofilm formation and vancomycin susceptibility of methicillin-resistant Staphylococcus aureus (MRSA) strains isolated from dairy cows with mastitis. Results In this study, the aqueous extracts of stigmata maydis inhibited the biofilm formation ability of MRSA strains and increased the vancomycin susceptibility of the strains under biofilm-cultured conditions. Conclusion This study proves that the aqueous extracts of stigmata maydis inhibit the biofilm formation ability of MRSA strains and increase the vancomycin susceptibility of the MRSA strains under biofilm-cultured conditions.【 授权许可】
CC BY
【 预 览 】
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