Oral manifestations in young adults infected with COVID-19 and impact of smoking: a multi-country cross-sectional study

PeerJ

article

Maha El Tantawi¹  Heba Jafar Sabbagh²  Nada Abubakor Alkhateeb³  Maryam Quritum¹  Joud Abourdan⁴  Nafeesa Qureshi⁵  Shabnum Qureshi⁶  Ahmed Hamoud⁷  Nada Mahmoud⁸  Ruba Odeh⁹  Nuraldeen Maher Al-Khanati^1,10  Rawiah Jaber^1,11  Abdulrahman Loaie Balkhoyor^1,12  Mohammed Shabi^1,13  Morenike O. Folayan^1,14  Noha Gomaa^1,15  Raqiya Al_Nahdi^1,16  Nawal Mahmoud^1,17  Hanane El Wazziki^1,18  Manal Alnaas^1,19  Bahia Samodien^2,20  Rawa Mahmoud^2,21  Nour Abu Assab^2,22  Sherin Saad^2,23  Sondos Al-Hachim^2,24  Ali Alshaikh^2,25  Wafaa Abdelaziz¹ 

[1] Department of Pediatric Dentistry and Dental Public Health, Faculty of Dentistry, Alexandria University;Department of Pediatric Dentistry, Faculty of Dentistry, King Abdulaziz University;Faculty of Medicine, King Abdulaziz University;Medical Faculty, Istanbul Medipol University;City Quay Dental Practice and Implant Centre;Department of Education, University of Kashmir;Faculty of Dentistry, Alexandria University;Faculty of Dentistry, National Ribat University;College of Dentistry, Ajman University;Department of Oral and Maxillofacial Surgery/Faculty of Dentistry, Syrian Private University;General Courses, King Abdulaziz University;Faculty of Engineering, King Abdulaziz University;King Saud bin Abdulaziz University for Health Sciences;Obafemi Awolowo University;Schulich School of Medicine and Dentistry, University of Western Ontario;Department of Dental Surgery, Oman Dental College;UCSI University;Department of Cereal Plant Pathology, National Institute of Aricultural Research;Division of Imaging Science and Technology, School of Medicine, University of Dundee;Western Cape Education Department;International Medical Center;Schools of Awqaf;Gothenburg University;Health Education Services;Faculty of Dentistry, King Abdulaziz University

关键词: COVID-19;    Oral lesions;    Smoking;    Dry mouth;   

DOI  :  10.7717/peerj.13555

学科分类：社会科学、人文和艺术（综合）

来源: Inra

【 摘 要 】

Background Oral manifestations and lesions could adversely impact the quality of people’s lives. COVID-19 infection may interact with smoking and the impact on oral manifestations is yet to be discovered. Objectives The aim of this study was to assess the self-reported presence of oral lesions by COVID-19-infected young adults and the differences in the association between oral lesions and COVID-19 infection in smokers and non-smokers. Methods This cross-sectional multi-country study recruited 18-to-23-year-old adults. A validated questionnaire was used to collect data on COVID-19-infection status, smoking and the presence of oral lesions (dry mouth, change in taste, and others) using an online platform. Multi-level logistic regression was used to assess the associations between the oral lesions and COVID-19 infection; the modifying effect of smoking on the associations.Results Data was available from 5,342 respondents from 43 countries. Of these, 8.1% reported COVID-19-infection, 42.7% had oral manifestations and 12.3% were smokers. A significantly greater percentage of participants with COVID-19-infection reported dry mouth and change in taste than non-infected participants. Dry mouth (11.1% vs 7.5%, p = 0.009) and change in taste (11.5% vs 2.7%, p < 0.001) were greater in COVID-19 infected than non-infected persons. The association between COVID-19-infection and dry mouth was stronger among smokers than non-smokers (AOR = 1.26 and 1.03, p = 0.09) while the association with change in taste was stronger among non-smokers (AOR = 1.22 and 1.13, p = 0.86). Conclusion Dry mouth and changed taste may be used as an indicator for COVID-19 infection in low COVID-19-testing environments. Smoking may modify the association between some oral lesions and COVID-19-infection.

【 授权许可】

CC BY