Double Trouble: Interrupting DAPT and COVID-19

Journal Of Cardiovascular Emergencies

article

Theofana Mihăilă¹  Aurelian Roșca¹  Bianca Ion¹ 

[1] “George Emil Palade” University of Medicine, Pharmacy, Science and Technology;Clinic of Cardiology, Emergency Clinical County Hospital

关键词: COVID-19;    stent thrombosis;    dual antiplatelet therapy;    hypercoagulability;   

DOI  :  10.2478/jce-2022-0007

学科分类：社会科学、人文和艺术（综合）

来源: Walter de Gruyter GmbH

【 摘 要 】

Cardiovascular disorders have been described as relevant risk factor for severe COVID infection. Stent thrombosis is a life-threatening complication that may occur subacutely. We present an interesting case of a middle-aged woman who developed acute stent thrombosis while interrupting dual antiplatelet therapy (DAPT) ticagrelor, during an episode of coronavirus disease (COVID-19). In our case, the patient’s not-compliance to DAPT, associated with COVID-19 infection and a hyperinflammatory and hypercoagulable state associated with it played a major role in the development of stent thrombosis. The hypercoagulable and hyperinflammatory state associated with COVID-19 has important implications for cardiac patients, especially those undergoing complex coronary intervention, predisposing them to an increased risk of post-PCI complications.

【 授权许可】

CC BY-NC-ND