The possible link between periodontitis and orodigestive cancer: An overview

Indian Journal of Dental Sciences

article

Siddharth Mallapragada¹  Himani Sharma¹  Stuti Gupta¹ 

[1] Department of Periodontology, School of Dental Sciences, Sharda University

关键词: Fusobacterium nucleatum;    orodigestive cancer;    periodontitis;    Porphyromonas gingivalis;    Treponema denticola;   

DOI  :  10.4103/IJDS.IJDS_115_19

学科分类：生物科学（综合）

来源: Wolters Kluwer Medknow Publications

【 摘 要 】

Increasing evidences are found in the literature lately regarding the association between periodontitis and orodigestive tract cancers. Periodontopathic bacteria resulting in periodontal disease, acts as a risk factor for the initiation and development of carcinoma. They have been shown to act through various mechanisms including inhibition of apoptosis, activation of cellular proliferation, and others. This review is an attempt to find the possible connecting mechanism between the aforesaid.

【 授权许可】

CC BY-NC-SA