OID-05. Arrangement of the blood donor registry typed for the red blood cell antigens

Cellular Therapy and Transplantation

article

Natalia V. Mineeva¹  Svetlana V. Gavrovskaya¹  Irina I. Krobinets¹  Elena A. Sysoeva¹  Natalia N. Bodrova¹ 

[1] Russian Research Institute of Hematology and Transfusiology

关键词: Registry;    donors;    erythrocyte antigens.;   

DOI  :  10.18620/ctt-1866-8836-2022-11-3-1-132

学科分类：肿瘤学

来源: Universitaetsklinikum Hamburg - Eppendorf / University Medical Center Hamburg - Eppendorf

【 摘 要 】

Among patients in need of transfusions there are people with rare erythrocyte antigens. In case of urgent transfusion there may be no compatible blood components available due to erythrocyte antigens mismatch. Also, antibodies directed against erythrocyte antigens may be a problem. There are a lot of sensitized individuals among hematological and oncohaematological patients, e.g. for those with thalassemia and sickle cell anemia it may be as high as 30%. The creation of blood donors registry containing blood typed by erythrocyte antigens may be a solution to donor/recipient pair matching problem. Since 2018 a registry of blood donors with RH, Kell, Kidd, Duffy, MNS, and Dombrock erythrocyte antigens typed functions in Russian NIIGT. We aimed to evaluate the occurrence of most clinically significant erythrocyte antigens of the RH, Kell, Kidd, Duffy, MNS, and Dombrock systems in registry donors.

【 授权许可】

CC BY