Self-Assembly Peptides-a Review

Online journal of biological sciences

article

Olushola Sunday Ayanda¹  Olusola Solomon Amodu²  Cyprian Yameso Abasi³  Michael John Klink⁴  Simphiwe Maurice Nelana⁴  Olatunde Stephen Olatunji⁵ 

[1]Department of Chemistry, Faculty of Science, Federal University Oye-Ekiti

[2]Department of Chemical Engineering, College of Engineering, Lagos State University of Science and Technology

[3]Department of Chemical Sciences, Faculty of Science, Niger Delta University

[4]Department of Chemistry, Faculty of Applied and Computer Sciences, Vaal University of Technology

[5]School of Chemistry and Physics, College of Agriculture, Engineering and Science, University of KwaZulu-Natal

关键词: Biomolecules;    Self-Assembled Peptide;    Nanostructure;    Nanotechnology;   

DOI  :  10.3844/ojbsci.2022.309.322

学科分类：生物科学（综合）

来源: Science Publications

【 摘 要 】

Self-assemblingof peptides is a spontaneous process by which peptides are self-organized toform well-ordered structures by intramolecular and intermolecular interactions.This process is controlled by the balance of the forces (attractive andrepulsive) within the peptide molecules. Notable methods used for the synthesisof self-assembly peptides are solid-phase synthesis, liquid-phase synthesis,recombinant technology, and the use of external fields. The self-assembled nanostructure-basedpeptides offer remarkable advantages; such as mild synthesis conditions, relativelysimple functionalization, fast synthesis, and low cost, resulting in theirremarkable potential for use in biosensors, imaging tools, antimicrobialagents, drug delivery systems, bioelectronics, tissue reparation. Herein, wepresent the origin of self-assembled peptides, synthesis of novel materialsproduced through self-assembly of peptides, structural elucidation,applications, recent trends, and the future outlook of self-assembly peptides.

【 授权许可】

CC BY