The Mechanism of Actions for Herbal Bioenhancers

RGUHS Journal of Pharmaceutical Sciences

article

Ashoka Shenoy M¹  Nitin Mahurkar² 

[1]Dept. of Pharmacology, Srinivas College of Pharmacy

[2]Department of Pharmacology, HKES’s MTRIPS, Kalaburagi – 585105.

关键词: Bioenhancer;    Bioavailability;    Piperine;    Niaziridin;    Curcumin;    Glycyrrhizin.;   

DOI  :  10.26463/rjps.11_2_7

学科分类：药学、药理学、毒理学（综合）

来源: Rajiv Gandhi University of Health Sciences

【 摘 要 】

Herbal bioenhancers do not possess their own inherent pharmacological activity, but when coadministered with other drugs, enhances their bioavailability and thus the efficacy. The interest for bioenhancers arises because of the chemotherapeutic agents which are poorly bioavailable and administered for prolonged periods, which can be toxic and expensive. One of the unique ways to achieve reduction in drug dosage and thereby drug toxicity and cost is to increase the bioavailability of drug. The present pharmaceutical research is more concerned with different aspects of exploring new chemical molecules having new modes of action. New drug development technologies were developed from the economics of treatment. There is a revolutionary shift in the way medicines are administered due to recent developments in enhancing the bioavailability. The present global focus is on methods aimed at reducing drug treatment period, leading to decrease in drug treatment cost. The reduction in cost of therapy will make the treatment more affordable for the financially challenged sections of the society.   Herbal bioenhancers do not possess their own inherent pharmacological activity, but when coadministered with other drugs, enhances their bioavailability and thus the efficacy. The interest for bioenhancers arises because of the chemotherapeutic agents which are poorly bioavailable and administered for prolonged periods, which can be toxic and expensive. One of the unique ways to achieve reduction in drug dosage and thereby drug toxicity and cost is to increase the bioavailability of drug. The present pharmaceutical research is more concerned with different aspects of exploring new chemical molecules having new modes of action. New drug development technologies were developed from the economics of treatment. There is a revolutionary shift in the way medicines are administered due to recent developments in enhancing the bioavailability. The present global focus is on methods aimed at reducing drug treatment period, leading to decrease in drug treatment cost. The reduction in cost of therapy will make the treatment more affordable for the financially challenged sections of the society.

【 授权许可】

CC BY