Two-Year Seroprevalence Surveys of SARS-CoV-2 Antibodies among Outpatients and Healthcare Workers in Ehime, Japan

Japanese journal of infectious diseases

article

Koichiro Suemori¹  Yumi Taniguchi²  Ai Okamoto²  Akiko Murakami²  Fumihiro Ochi³  Harutaka Aono⁴  Naohito Hato⁵  Haruhiko Osawa⁶  Hitoshi Miyamoto²  Takashi Sugiyama⁷  Masakatsu Yamashita⁸  Hisamichi Tauchi³  Katsuto Takenaka¹ 

[1] Department of Hematology, Clinical Immunology and Infectious Diseases, Ehime University Graduate School of Medicine;Clinical Laboratory Department, Ehime University Hospital;Department of Pediatrics, Ehime University Graduate School of Medicine;Division of Nursing, Ehime University Hospital;Department of Otolaryngology, Head and Neck Surgery, Ehime University Graduate School of Medicine;Department of Diabetes and Molecular Genetics, Ehime University Graduate School of Medicine;Department of Obstetrics and Gynecology, Ehime University Graduate School of Medicine;Department of Immunology, Ehime University Graduate School of Medicine

关键词: seroprevalence;    SARS-CoV-2;    antibody;    outpatient;    healthcare worker;   

DOI  :  10.7883/yoken.JJID.2022.155

学科分类：传染病学

来源: National Institute of Infectious Diseases

【 摘 要 】

We conducted two-year seroprevalence surveys of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies among outpatients and healthcare workers (HCWs) at Ehime University Hospital. Data were collected for outpatients and HCWs in June 2020 (1st survey), December 2020 (2nd survey), July 2021 (3rd survey), and December 2021 (4th survey), focusing on demographics, occupation, and the seroprevalence of anti-SARS-CoV-2 antibodies. Blood samples were obtained from randomly selected outpatients who visited our hospital for medical care and HCWs undergoing regular medical checks with opt-out informed consent. SARS-CoV-2 antibody positivity was evaluated using two laboratory-based quantitative tests. The total number of participants enrolled was 6,369 (1st survey: 1,000 outpatients and 743 HCWs, 2nd survey: 1,000 outpatients and 407 HCWs, 3rd survey: 1,000 outpatients and 804 HCWs, 4th survey: 1,000 outpatients and 415 HCWs). The prevalence of SARS-CoV-2 antibodies among outpatients and HCWs was 0–0.1% and 0–0.124% during the research period, respectively, and changed little over time. These findings suggest that the magnitude of COVID-19 infection during the pandemic among outpatients and HCWs in this rural hospital might have been small.

【 授权许可】

Unknown