Rubella Seroprevalence among the General Population in Dongguan, China

Japanese Journal of Infectious Diseases

Dong Wang²  Yongzhen Xiong¹  Hao Tang¹  Weiyan Lin³  Jindong Ni³  Zhengfa Liao³ 

[1] Department of School Clinic, Guangdong Medical College;Department of Immunization Program, Dongguan Center for Disease Control and Prevention;Department of Epidemiology and Biostatistics, Guangdong Medical College

关键词: rubella;    seroprevalence;    vaccination;    antibody;   

DOI  :  10.7883/yoken.JJID.2014.255

学科分类：传染病学

来源: National Institute of Infectious Diseases

【 摘 要 】

References(22)In order to assess the immunity to rubella infection in Dongguan, China, we conducted a seroprevalence survey on rubella and used ELISA to measure rubella-specific IgG in serum samples. A total of 1,017 individuals aged 0–59 years were selected by multistage cluster sampling. Among them, 904 (88.9%) were seropositive for rubella. Two groups (20–29 and ≥40 years) had seropositivity rates of <90%. In comparison with participants aged ≥20 years, rubella immunization rates were higher in those aged <20 years (83.2% vs. 93.7%, respectively; χ2 = 28.063, P < 0.001). Among women aged 20–29 years, only 63.8% had antibodies above the protective level. Multivariate analysis revealed that only sex and age were significantly associated with rubella-protective antibody levels. Our results suggest that in the study area, women of childbearing age had a greater serological susceptibility to rubella. Additional vaccinations for rubella of susceptible young adults should be considered, particularly in women of childbearing age.

【 授权许可】

Unknown