Clinical and Para-clinical Findings of COVID19 in Hemodialysis Patients Compared to Control Group: A Case-Control Study

Nephro-Urology Monthly

article

Elham Shahreki¹  AliReza Ansari-Moghaddam²  Roya Alavi Naini³  Maryam Keikha⁴  Ramin Bazi⁵  Ahmad Reza Shahraki⁶ 

[1] Department of Internal Medicine, Nephrology, Ali Ibne Abitaleb Hospital, Zahedan University of Medical Sciences;Health Promotion Research Center, Zahedan University of Medical Sciences;Infectious Diseases and Tropical Medicine Research Center, Resistant Tuberculosis Institute, Zahedan University of Medical Sciences;Department of Radiology, Children and Adolescents Health Research Center Zahedan University of Medical Sciences;School of Medicine, Zahedan University of Medical Sciences;Department of Surgery, Zahedan University of Medical Sciences

关键词: COVID-19;    Hemodialysis;    Chronic Kidney Disease;    SARS-CoV-2;   

DOI  :  10.5812/numonthly-122095

学科分类：基础医学

来源: Kowsar Corporation

【 摘 要 】

Background: Following the global outbreak of severe acute respiratory syndrome coronavirus 2 in different communities, hemodialysis patients have not been spared by this viral infection. Objectives: This study evaluated the clinical symptoms laboratory and imaging findings in patients undergoing hemodialysis and compared these characteristics with the control group. Methods: The study was performed on 72 patients with positive COVID-19 polymerase chain reaction test, of whom 36 cases had end-stage renal disease undergoing hemodialysis and the remaining had no history of kidney diseases. After matching the two groups in terms of age, sex, and other underlying diseases, the clinical, laboratory, and chest computed tomography (CT) scan findings were compared between the case and control groups. Results: The mean age of dialysis patients was 42.52 ± 12.10 years and 48.58 ± 17.35 years in the control group. The study results revealed that hemodialysis patients had less fever, cough, and shortness of breath than the control group (P-value < 0.05). Hemoglobin, lymphocyte, and platelet counts were significantly lower in hemodialysis patients in comparison to the control group (P-value < 0.05). C-reactive protein was significantly higher in patients undergoing hemodialysis (P-value 0.05). Conclusions: Hemodialysis patients had fewer initial clinical symptoms but more abnormalities in laboratory findings and ground-glass opacities on chest CT scans and a higher mortality rate.

【 授权许可】

Unknown