Systematic review of clinical practice guidelines for uveitis

BMJ Open Ophthalmology

article

Nima Ghadiri¹  Ian R Reekie³  Iris Gordon⁴  Sare Safi⁶  Gareth Lingham⁷  Jennifer R Evans⁹  Stuart Keel^1,11 

[1] Department of Ophthalmology , Liverpool University Hospitals NHS Foundation Trust;Department of Eye and Vision Science , University of Liverpool;Kennedy Institute of Rheumatology , University of Oxford;Centre for Public Health , Queen's University Belfast;International Centre for Eye Health , London School of Hygiene and Tropical Medicine International Centre for Eye Health;Ophthalmic Epidemiology Research Center, Research Institute for Ophthalmology and Vision Science , Shahid Beheshti University of Medical Sciences;Centre for Eye Research Ireland , Technological University Dublin;Centre for Ophthalmology and Visual Science , Lions Eye Institute, The University of Western Australia;Centre for Public Health , Queen’s University Belfast UK;International Centre for Eye Health , London School of Hygiene and Tropical Medicine;Department of Noncommunicable Diseases, Vision and Blindness Prevention Programme , World Health Organization

关键词: Inflammation;    Public health;    Retina;    Treatment other;    Treatment Medical;    Epidemiology;   

DOI  :  10.1136/bmjophth-2022-001091

学科分类：工业工程学

来源: BMJ Publishing Group

【 摘 要 】

To facilitate the integration of eye care into universal health coverage, the WHO is developing a Package of Eye Care Interventions (PECI). Development of the PECI involves the identification of evidence-based interventions from relevant clinical practice guidelines (CPGs) for uveitis.A systematic review of CPGs published on uveitis between 2010 and March 2020 was conducted. CPGs passing title and abstract and full-text screening were evaluated using the Appraisal of Guidelines for Research and Evaluation II (AGREE II) tool and data on recommended interventions extracted using a standard data extraction sheet.Of 56 CPGs identified as potentially relevant from the systematic literature search, 3 CPGs underwent data extraction following the screening stages and appraisal with the AGREE II tool. These CPGs covered screening for, monitoring and treating juvenile idiopathic arthritis (JIA)-associated uveitis, the use of adalimumab and dexamethasone in treating non-infectious uveitis, and a top-level summary of assessment, differential diagnosis and referral recommendations for uveitis, aimed at primary care practitioners. Many of the recommendations were based on expert opinion, though some incorporated clinical study and randomised controlled trial data.There is currently sparse coverage of the spectrum of disease caused by uveitis within CPGs. This may partially be due to the large number of conditions with diverse causes and clinical presentations covered by the umbrella term uveitis, which makes numerous sets of guidelines necessary. The limited pool of CPGs to select from has implications for clinicians seeking guidance on clinical care strategies for uveitis.InflammationPublic healthRetinaTreatment otherTreatment MedicalEpidemiologyhttp://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

【 授权许可】

CC BY-NC|CC BY|CC BY-NC-ND