Translation and evaluation of psychometric properties of the Amharic pediatric quality of life inventory 4.0 generic core scale for children with cancer

Health and Quality of Life Outcomes

Research

Kai Chow Choi¹  William Ho Cheung Li¹  Janita Pak Chun Chau¹  Tenaw Gualu Melesse²  Abdulkadir Mohamed Said Gidey³  Mulugeta Ayalew Yimer⁴ 

[1] Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR;Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR;Department of Pediatrics and Child Health Nursing, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia;Pediatric Hematology-Oncology Division, Department of Pediatrics and Child Health, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia;Pediatric Hematology-Oncology Unit, Department of Pediatrics and Child Health, School of Medicine, University of Gondar, Gondar, Ethiopia;

关键词: Cancer;    Child;    Health-related quality of life;    Quality of life;    Psychometrics;    Reliability;    Validity;   

DOI  :  10.1186/s12955-022-02077-8

 received in 2022-10-19, accepted in 2022-12-02,  发布年份 2022

来源: Springer

【 摘 要 】

BackgroundChildhood cancer negatively impacts a child's physical, mental, and behavioural health and significantly affects their health-related quality of life. The Pediatric Quality of Life Inventory 4.0 Generic Core Scale (PedsQL™ 4.0 GCS) is one of the most commonly used measures of the quality of life in children. However, the Amharic version of PedsQL™ 4.0 GCS has not been validated in a paediatric oncology population. This study aimed to translate and evaluate the psychometric properties of the Amharic PedsQL™ 4.0 GCS (PedsQL™ 4.0 GCS (A)) for Ethiopian children with cancer.MethodsA descriptive cross-sectional study was conducted among children aged 8–18 years with any type of cancer across the cancer trajectory. Cronbach’s alpha and intraclass correlation coefficient were computed to determine the internal consistency and test-retest reliability of the scale. The convergent validity was established by examining the correlation of the PedsQL™ 4.0 GCS (A) with the Amharic version of the Revised Child Anxiety and Depression Scale (RCADS-25(A)). Factorial validity was evaluated by conducting a confirmatory factor analysis.ResultsThe study included 142 participants with childhood cancer. PedsQL™ 4.0 GCS (A) had good validity and reliability. It demonstrated high internal consistency with a Cronbach’s alpha of 0.96 for the scale and 0.82–0.95 for the subscales. The intraclass correlation coefficient for the scale was 0.9 and that for the subscales was 0.76–0.90. The PedsQL™ 4.0 GCS (A) was highly correlated with RCADS-25 (A) (r = − 0.97, p < 0.001), supporting its convergent validity. The four-factor structure of the model fitted the data satisfactorily (χ2/df = 1.28; CFI = 0.97; TLI = 0.97; RMSEA = 0.05; SRMR = 0.05), supporting the factorial validity of the PedsQL™ 4.0 GCS (A).ConclusionThe PedsQL™ 4.0 GCS (A) demonstrates desirable psychometric properties for assessing quality of life among Ethiopian children with cancer. The scale can be used in clinical settings for assessing and evaluating quality of life in children with cancer. The use of parent-report versions and studies in those with different health conditions and healthy populations are necessary to further establish the psychometric properties of the PedsQL™ 4.0 GCS (A).

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

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