A prospective analysis of optimal total weight gain ranges and trimester-specific weight gain rates for Chinese pregnant women

BMC Pregnancy and Childbirth

Research

Dagang Yang¹  Yunhui Gong²  Toshio Shimokawa³  Ke Wan³  Kun Zou⁴  Lingli Zhang⁴  Linan Zeng⁴  Yujie Xu⁵  Guo Cheng⁵  Yue Chen⁶  Yidi Wang⁷  Li Zhao⁷  Jingyuan Xiong⁷ 

[1] Department of Clinical Nutrition, Affiliated Hospital of Guizhou Medical University, Guiyang, China;Department of Gynaecology, West China Women’s and Children’s Hospital, Sichuan University, Chengdu, China;Department of Medical Data-science, Graduate School of Medicine, Wakayama Medical University, Wakayama, Japan;Department of Pharmacy, Evidence-Based Pharmacy Center, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), West China Women’s and Children’s Hospital, Sichuan University, Chengdu, China;Laboratory of Molecular Translational Medicine, Center for Translational Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Department of Pediatrics, West China Women’s and Children’s Hospital, Sichuan University, Chengdu, China;School of Public Health, Southwest Medical University, Luzhou, China;West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China;

关键词: Gestational weight gain;    Advanced maternal age;    Gestational diabetes mellitus;    Preeclampsia;    Preterm birth;    Cesarean delivery;    Large for gestational age;    Macrosomia;    Small for gestational age;    Stillbirth;   

DOI  :  10.1186/s12884-023-05398-8

 received in 2022-08-26, accepted in 2023-01-20,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundGestational weight gain (GWG) criteria recommended by the Institute of Medicine may not be appropriate for Asians. Our aims are to investigate the association between GWG and adverse pregnancy outcomes, and to propose optimal total GWG and rates of GWG for Chinese women.MethodsProspective data of 51,125 mother-child pairs from 27 hospitals and community health care centers from Guizhou, Yunnan and Sichuan provinces in China between 2014 and 2018 were analyzed. Generalized Additive Models were performed to determine the associations of GWG with the risk of aggregated adverse outcomes (gestational diabetes mellitus, preeclampsia, cesarean delivery, stillbirth, preterm birth, macrosomia, large for gestational age, and small for gestational age). The range that did not exceed a 2.5% increase from the lowest risk of aggregated adverse outcomes was defined as the optimal GWG range.ResultsAmong all participants, U-shaped prospective association was found between GWG and the risk of aggregated adverse pregnancy outcomes. The optimal GWG range of 8.2–13.0 kg was proposed for underweight, 7.3–12.5 kg for normal weight, and 2.0–9.4 kg for overweight/obese women. Meanwhile, a higher GWG rate in the first two trimesters than that in the last trimester was suggested, except for overweight/obese women. After stratified by maternal age, mothers ≥35 years were suggested to gain less weight compared to younger mothers.ConclusionsTo keep a balance between maternal health and neonatal growth, optimal GWG ranges based on Asia-specific BMI categories was suggested for Chinese women with different pre-gravid BMIs and maternal ages.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

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