期刊论文

【摘要】

Host defense peptides (HDPs) are small molecules with broad-spectrum antimicrobial activities against infectious bacteria, viruses, and fungi. Increasing evidence suggests that HDPs can also indirectly protect hosts by modulating their immune responses. Due to these dual roles, HDPs have been considered one of the most promising antibiotic substitutes to improve growth performance, intestinal health, and immunity in farm animals. This review describes the antimicrobial and immunomodulatory roles of host defense peptides and their recent applications in animal production.

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CC BY
© The Author(s) 2022

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Journal of Animal Science and Biotechnology
The dual antimicrobial and immunomodulatory roles of host defense peptides and their applications in animal production
Review
Di Wu¹ Linglong Fu¹ Weizhang Wen¹ Na Dong¹
[1] State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, 100193, Beijing, China;
关键词: Antimicrobials; Host defense peptides; Immunomodulation; Poultry; Ruminants; Swine;
DOI : 10.1186/s40104-022-00796-y
received in 2022-05-27, accepted in 2022-10-11, 发布年份 2022
来源: Springer
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