Common Diabetogenic Agents Used in Experimental Animals: A Review

Journal of applied sciences research

article

Isam M Abu Zeid¹ 

[1] Department of Biological Sciences, Faculty of Sciences, King Abdulaziz University;Princess Dr Najla Bint Saud Al-Saud Center for Excellence Research in Biotechnology, King Abdulaziz University

关键词: Diabetes;    Diabetogenic agents;    Animals;    Streptozotocin;    Alloxan;   

DOI  :  10.22587/jasr.2019.15.5.5

学科分类：社会科学、人文和艺术（综合）

来源: AENSI

【 摘 要 】

Diabetes mellitus is a complex metabolic disorder marked by a chronic hyperglycaemic status generated because of insulin secretion deficiency; resistance to insulin effect or both. Screening models are essential in offering insights without invasive processes in humans. Disease introduction on a target cell model needs a clear investigation so that complication of treatment can be established. The induction of diabetes mellitus aims to use animals under replica insulin deficiency or insensitivity similar to human physiology. This review provides useful information on the common synthetic chemicals that emerge as diabetogenic agents.

【 授权许可】

Unknown