Contrast-enhanced ultrasonography for the diagnosis of spontaneous necrosis of hepatocellular carcinoma: A report of 2 cases

Radiology Case Reports

article

Yu Ota¹  Kazunobu Aso¹  Shin Otake¹  Mitsuyoshi Okada¹  Kounosuke Shukuda¹  Koji Sawada¹  Hideki Yokoo¹  Mishie Tanino¹  Mikihiro Fujiya¹  Toshikatsu Okumura¹ 

[1] Division of Metabolism and Biosystemic Science, Gastroenterology, and Hematology/Oncology, Department of Medicine, Asahikawa Medical University

关键词: Hepatocellular carcinoma;    Spontaneous necrosis;    Contrast-enhanced ultrasonography;    Sonazoid;   

DOI  :  10.1016/j.radcr.2022.10.019

学科分类：生物化学工程

来源: University of Washington * Department of Radiology

【 摘 要 】

Spontaneous necrosis of hepatocellular carcinoma (HCC) is rare and difficult to diagnose preoperatively if it occurs before the definitive diagnosis of HCC; this is because spontaneous necrosis of HCC exhibits various patterns in imaging studies. We compared imaging and pathological findings, and examined the possibility of diagnosing spontaneous necrosis of HCC using contrast-enhanced ultrasonography (CEUS). We experienced 2 cases of spontaneous necrosis of HCC. In case 1, spontaneous necrosis occurred after HCC diagnosis, while in case 2 it occurred before the first admission. The tumor in case 2 contained internal nodules and outer fibrous tissue. CEUS revealed a vascular spot in the hypovascular area during the vascular phase and a complete defect during the Kupffer phase. These findings accorded with the pathological findings and may be important for diagnosing spontaneous necrosis of HCC.

【 授权许可】

CC BY|CC BY-NC-ND