Performance of NEWS, qSOFA, and SIRS Scores for Assessing Mortality, Early Bacterial Infection, and Admission to ICU in COVID-19 Patients in the Emergency Department

Frontiers in Medicine

article

Julio Alencar¹  Luz Marina Gómez Gómez¹  Andre Lazzeri Cortez²  Heraldo Possolo de Souza¹  Anna Sara Levin²  Matias Chiarastelli Salomão² 

[1] Departamento de Emergência Médica, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo;Departamento de Moléstias Infecciosas e Parasitárias do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo;Departamento de Emergência Médica, Faculdade de Medicina, Universidade de São Paulo;Departamento de Moléstias Infecciosas e Parasitárias, Faculdade de Medicina, Universidade de São Paulo

关键词: COVID-19;    sepsis;    NEWS;    qSOFA (quick sequential organ failure assessment);    SIRS (for Systemic Inflammatory Response Syndrome);    scores;    prognosis;    emergency;   

DOI  :  10.3389/fmed.2022.779516

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

SARS-CoV-2 infection has a wide spectrum of presentations, from asymptomatic to pneumonia and sepsis. Risk scores have been used as triggers for protocols that combine several interventions for early management of sepsis. This study tested the accuracy of the score SIRS, qSOFA, and NEWS in predicting outcomes, including mortality and bacterial infection, in patients admitted to the emergency department (ED) during the COVID-19 pandemic. We described 2,473 cases of COVID-19 admitted to the ED of the largest referral hospital for severe COVID-19 in Brazil during the pandemic. SIRS, qSOFA and NEWS scores showed a poor performance as prognostic scores. However, NEWS score had a high sensitivity to predict in-hospital death (0.851), early bacterial infection (0.851), and ICU admission (0.868), suggesting that it may be a good screening tool for severe cases of COVID-19, despite its low specificity.

【 授权许可】

CC BY