Lab-Based Filtration System Improving Recovery and Reducing Time to Detection for Diagnosis of Sepsis

sepsis;blood stream infection;blood culture;filtration;time to detection;TTD;turbidity;bacteria;infection;filter membrane;Materials Science & Engineering

Beamesderfer, Andrew CMao, Hai-Quan ;

Johns Hopkins University

关键词: sepsis;    blood stream infection;    blood culture;    filtration;    time to detection;    TTD;    turbidity;    bacteria;    infection;    filter membrane;    Materials Science & Engineering;   

Others  :  https://jscholarship.library.jhu.edu/bitstream/handle/1774.2/58698/BEAMESDERFER-THESIS-2017.pdf?sequence=1&isAllowed=y

瑞士|英语

来源: JOHNS HOPKINS DSpace Repository

【 摘 要 】

Rapid and accurate detection of a blood stream infection is critical for the proper management of patients displaying symptoms of sepsis. Current blood culture systems are both time consuming and may yield low recovery in the presence of antibiotics, delaying needed results for effective sepsis management. To improve recovery rates and time to detection, a novel sample preparation and culture device system was created. The design concentrates the microorganisms into a small volume, while removing antibiotics and inhibitory blood components. This system allows for both increased recovery and decreased time to detection, granting rapid and accurate detection of blood stream infections to help clinicians diagnose septicemia.