Status and Influencing Factors of Parenteral Nutrition Practice for Late Preterm Infants in China

Frontiers in Pediatrics

article

Meiying Quan¹  Zhenghong Li¹  Danhua Wang¹  Kurt Schibler²  Li Yang³  Jie Liu⁴  Xuanguang Qin⁵  Xin Zhang⁶  Tongyan Han⁷  Ying Li⁸ 

[1] Peking Union Medical College Hospital, Department of Pediatrics;Cincinnati Children’s Hospital Medical Center, Cincinnati;Department of Pediatrics, Beijing Tongzhou District Maternal and Child Health Hospital;Department of Pediatrics, The People’s Hospital of Beijing University;Department of Pediatrics, Beijing Chaoyang Hospital;Department of Pediatrics, Peking University First Hospital;Department of Pediatrics, Peking University Third Hospital;Department of Pediatrics, Beijing Haidian District Maternal and Child Health Hospital

关键词: late preterm infants;    parenteral nutrition;    influencing factors;    growth;    amino acid;    lipid emulsion;   

DOI  :  10.3389/fped.2022.844460

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Objectives To explore the status of parental nutrition practice of hospitalized late preterm infants and the factors influencing the clinical prescription. Methods A multi-center, prospective cohort study was conducted during October 2015 to October 2017. Infants born after 34 weeks and before 37 weeks were enrolled from twenty-five hospitals in the Beijing area of China. Data of enteral and parenteral nutrition were collected. Results A total of 1,463 late preterm infants were enrolled in this study, 53.9% of infants were supported by parenteral nutrition. Over 60% of 34 weeks’ infants were on parenteral nutrition during the 2nd to the 4th day. Logistic regression analysis showed that gestational age(GA) (OR = 0.69, 95%CI 0.58–0.81), birth weight (OR = 0.41, 95%CI 0.26–0.65), hypoglycemia (OR = 2.77, 95%CI 1.90–4.04), small for gestational age (SGA) (OR = 2.18, 95%CI 1.34–3.55), feeding intolerance (OR = 6.41, 95%CI 1.90–21.59), neonatal respiratory distress syndrome (NRDS) (OR = 2.16, 95%CI 1.12–4.18), neonatal infection(OR = 1.56 95%CI 1.16–2.10), and slow enteral nutrition advancement rate (OR = 0.92, 95%CI 0.90–0.95) were factors influencing the administration of parenteral nutrition. Conclusion Over half of hospitalized late preterm infants were prescribed with parenteral nutrition. Infants with lower GA, lower birth weight, diagnosed with hypoglycemia, SGA, feeding intolerance, NRDS, neonatal infection, or a slower rate of enteral nutrition advancement had a higher likelihood of receiving parenteral nutrition.

【 授权许可】

CC BY