Circulating Phospholipids as Biomarkers of Breast Cancer: A Review

Breast Cancer: Basic and Clinical Research

Short Review

Dharmica April Haridatt Mistry¹  Peter William French² 

[1] BCAL Diagnostics Pty Ltd, Sydney, NSW, Australia.;BCAL Diagnostics Pty Ltd, Sydney, NSW, Australia.;School of Medicine, University of New South Wales, Kensington, NSW, Australia.;

关键词: breast cancer;    lipids;    phospholipids;    blood;    plasma;    biomarkers;   

DOI  :  10.4137/BCBCR.S40693

 received in 2016-08-08, accepted in 2016-09-15,  发布年份 2016

来源: Sage Journals

【 摘 要 】

Breast cancer is the most common cancer in women and the second leading cause of cancer deaths in women. The key to surviving breast cancer is early detection and treatment. Current technologies rely heavily on imaging of the breast, and although considered the gold standard, they have their limitations. There is a need for a more accurate screening test for women of all ages, which can detect the cancer at a cellular level and before metastasis. There have been extensive studies into markers for breast cancer including protein and nucleic acid biomarkers, but to date, these have been unsuccessful. A growing field of interest is the association between breast cancer (tissue and cells) and lipids, which is documented in the literature, and may be considered as a leading candidate in the breast cancer detection space.

【 授权许可】

CC BY-NC   
© 2016 SAGE Publications.

【 图 表 】

Figure 3.