期刊论文详细信息
Arabian Journal of Chemistry | |
Direct oxidation of Δ2-isoxazolines synthesis by metal ion-mediated diastereoface-selective 1,3-dipolar cycloaddition with “activated” DMSO | |
关键词: 1,3-Dipolar cycloaddition; Δ2-Isoxazol-6(6aH)-one; Δ2-Isoxazole-4,6(5H,6aH)-dione; Stereoselectivity; Swern oxidation; | |
DOI : 10.1016/j.arabjc.2012.12.008 | |
来源: DOAJ |
【 摘 要 】
A series of 4-hydroxyl-Δ2-isoxazol-6(6aH)-one derivatives was prepared by magnesium ion-mediated diastereoface-selective 1,3-dipolar cycloaddition of aromatic nitrile oxides with pyrrolidinone derivatives. The reaction of 4-hydroxyl-Δ2-isoxazol-6(6aH)-one derivatives with dimethylsulfoxide and oxalyl chloride under Swern conditions led to a Δ2-isoxazole-4,6(5H,6aH)-dione.
【 授权许可】
Unknown