Incidence and time-varying predictors of HIV and sexually transmitted infections among male sex workers in Mexico City

Infectious Diseases of Poverty

Don Operario¹  Marta Wilson-Barthes²  Mark N. Lurie²  Brandon D. L. Marshall²  Omar Galárraga³  Andrew R. Zullo³  Karla Y. Ganley⁴  Kenneth H. Mayer⁵  Santa García-Cisneros⁶  Sandra G. Sosa-Rubí⁶  Carlos J. Conde-Glez⁶ 

[1] Department of Behavioral and Social Science, School of Public Health, Brown University;Department of Epidemiology, School of Public Health, Brown University;Department of Health Services, Policy, and Practice, School of Public Health, Brown University;Department of Narrative Medicine, Columbia University;Fenway Health and Harvard University;National Institute of Public Health (INSP);

关键词: Male sex worker;    Men who have sex with men;    HIV;    Sexually transmitted infection;    Transmission;    Risk factor;   

DOI  :  10.1186/s40249-020-00792-2

来源: DOAJ

【 摘 要 】

Abstract Background Male sex workers are at high-risk for acquisition of sexually transmitted infections (STIs), including human immunodeficiency virus (HIV). We quantified incidence rates of STIs and identified their time-varying predictors among male sex workers in Mexico City. Methods From January 2012 to May 2014, male sex workers recruited from the largest HIV clinic and community sites in Mexico City were tested for chlamydia, gonorrhea, syphilis, hepatitis, and HIV at baseline, 6-months, and 12-months. Incidence rates with 95% bootstrapped confidence limits were calculated. We examined potential time-varying predictors using generalized estimating equations for a population averaged model. Results Among 227 male sex workers, median age was 24 and baseline HIV prevalence was 32%. Incidence rates (per 100 person-years) were as follows: HIV [5.23; 95% confidence interval (CI): 2.15–10.31], chlamydia (5.15; 95% CI: 2.58–9.34), gonorrhea (3.93; 95% CI: 1.88–7.83), syphilis (13.04; 95% CI: 8.24–19.94), hepatitis B (2.11; 95% CI: 0.53–4.89), hepatitis C (0.95; 95% CI: 0.00–3.16), any STI except HIV (30.99; 95% CI: 21.73–40.26), and any STI including HIV (50.08; 95% CI: 37.60–62.55). In the multivariable-adjusted model, incident STI (excluding HIV) were lower among those who reported consistently using condoms during anal and vaginal intercourse (odds ratio = 0.03, 95% CI: 0.00–0.68) compared to those who reported inconsistently using condoms during anal and vaginal intercourse. Conclusions Incidence of STIs is high among male sex workers in Mexico City. Consistent condom use is an important protective factor for STIs, and should be an important component of interventions to prevent incident infections.

【 授权许可】

Unknown