Injectable hydrogels for anti-tumour treatment: a review

Biosurface and Biotribology

Huan He¹  Xiong Lu¹  Chaoming Xie¹ 

[1] School of Materials Science and Engineering, Southwest Jiaotong University;

关键词: cancer;    cellular biophysics;    radiation therapy;    hyperthermia;    patient treatment;    hydrogels;    tumours;    anti-tumour treatment;    solid tumours;    loading anti-tumour materials;    anti-tumour injectable hydrogels;    gel-forming mechanism;    current anti-tumour methods;    anti-tumour mechanism;    tumour treatments;    anti-tumour therapy;   

DOI  :  10.1049/bsbt.2020.0020

来源: DOAJ

【 摘 要 】

Injectable hydrogels have become the material of choice for the treatment of solid tumours based on their advantages in loading anti-tumour materials. This study reviews the main scientific research achievements on anti-tumour injectable hydrogels in recent years. The gel-forming mechanism of anti-tumour injectable hydrogels was listed, and the advantages and difficulties of each gel-forming mechanism were summarised. In addition, several current anti-tumour methods based on injectable hydrogels were discussed, including chemotherapy, hyperthermia-based therapy, catalytic therapy and immune therapy, as well as the integration of diagnosis and treatment to monitor the progress of cancer treatment. The anti-tumour mechanism and the advantages and disadvantages of various tumour treatments were analysed. Finally, the future development trend of injectable hydrogels for anti-tumour therapy was discussed.

【 授权许可】

Unknown