Extrusion-Based 3D Printing for Highly Porous Alginate Materials Production

Gels

Andrey Abramov¹  Natalia Menshutina¹  Pavel Tsygankov¹  Daria Lovskaya¹ 

[1] International Science and Educational Center for Transfer of Pharmaceutical and Biotechnologies, Mendeleev University of Chemical Technology of Russia, Miusskaya pl. 9, 125047 Moscow, Russia;

关键词: 3D printing;    alginate;    thixotropic properties;    supercritical drying;   

DOI  :  10.3390/gels7030092

来源: DOAJ

【 摘 要 】

Three-dimensional (3D) printing is a promising technology for solving a wide range of problems: regenerative medicine, tissue engineering, chemistry, etc. One of the potential applications of additive technologies is the production of highly porous structures with complex geometries, while printing is carried out using gel-like materials. However, the implementation of precise gel printing is a difficult task due to the high requirements for “ink”. In this paper, we propose the use of gel-like materials based on sodium alginate as “ink” for the implementation of the developed technology of extrusion-based 3D printing. Rheological studies were carried out for the developed alginate ink compositions. The optimal rheological properties are gel-like materials based on 2 wt% sodium alginate and 0.2 wt% calcium chloride. The 3D-printed structures with complex geometry were successfully dried using supercritical drying. The resulting aerogels have a high specific surface area (from 350 to 422 m²/g) and a high pore volume (from 3 to 3.78 cm³/g).

【 授权许可】

Unknown