Investigation Into Environmental Selenium and Arsenic Levels and Arseniasis Prevalence in an Arsenic-Affected Coal-Burning Area

Frontiers in Nutrition

Dong-Yuan Cao¹  Wen-Hong Tan¹  Qian Li¹  Ai-Mei Bai²  Xiao-Qian Li²  Zhong-Xue Fan²  Yue Li²  Yi-Jun Kang³ 

[1] Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, Research Center of Stomatology, Xi’an Jiaotong University College of Stomatology, Xi’an, China;Key Laboratory of Trace Elements and Endemic Diseases of the National Health Commission, Shaanxi Provincial Institute For Endemic Disease Control, Xi’an, China;School of Public Health, Xi’an Jiaotong University Health Science Center, Xi’an, China;

关键词: arsenic;    selenium;    arsenic poisoning;    antagonism;    coal;   

DOI  :  10.3389/fnut.2022.922481

来源: DOAJ

【 摘 要 】

This study aims to explore whether selenium (Se) concentration correlates with arseniasis in a high-arsenic coal area in the southern Shaanxi Province, China. Herein, an epidemiological investigation was conducted among 100 arsenic (As)-poisoned patients in Ziyang County, an area with high soil As and Se levels. Fifty healthy subjects were selected from areas without endemic As poisoning. The subjects in the high-As coal area were diagnosed with either normal, suspicious, mild, moderate, or severe As poisoning. Local coal, water, soil, corn, and pepper samples, as well as hair, blood, and urine samples of subjects and patients were collected and analyzed for their As and Se contents. The contents of As and Se in coal, soil, corn, pepper, and hair samples from Ziyang County were significantly higher than those in the control area. The As content of hair in Ziyang County positively correlated with As poisoning, whereas the Se content of hair and urine negatively correlated with As poisoning. The Se content in the body was negatively correlated with the degree of As poisoning, indicating that Se may accelerate the metabolism and decumulation of As and antagonize As toxicity.

【 授权许可】

Unknown